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Hirschsprung’s Disease: A Historical Perspective – 1691–2018
Pages 1-17
The fourth edition of this leading book provides an authoritative, comprehensive and complete account of the neuronal disorders of the lower gastrointestinal tract in children. The book has been thoroughly revised and updated to reflect major advances that have occurred both in the understanding as well as the treatment of Hirschsprung’s disease.
Contents discuss the latest therapies such as stem cell therapies, the epidemiology and association with multiple endocrine neoplasia and approaches to diagnosis such as radiology and manometry as well as Hirschsprung’s disease in adolescents and adults.
Surgical approaches are thoroughly covered and include a new chapter on intestinal transplantation options. The follow-up care and long-term outcomes of patients who have undergone therapy are also addressed in this edition.
With several new chapters added and the contents updated and re-worked, this edition is authored by the leading current experts in their respective fields. It is a must-have book for pediatric surgeons, pediatricians, gastroenterologists, and colorectal surgeons.
Hirschsprung’s Disease: A Historical Perspective – 1691–2018
Pages 1-17
Development of the Enteric Nervous System
Pages 19-29
Functional Anatomy of the Enteric Nervous System
Pages 31-76
Normal Colonic Motor Function and Structure
Pages 77-95
Animal Models of Aganglionosis
Pages 97-113
Familial Hirschsprung’s Disease
Pages 115-119
Genetics of Hirschsprung’s Disease
Pages 121-131
Stem Cell Therapy for Enteric Neuropathies
Pages 133-152
Pathophysiology of Hirschsprung’s Disease
Pages 153-166
Epidemiology and Clinical Characteristics of Hirschsprung’s Disease
Pages 167-174
Congenital Anomalies and Genetic Associations in Hirschsprung’s Disease
Pages 175-199
Association Between Hirschsprung’s Disease and Multiple Endocrine Neoplasia
Pages 201-207
Hirschsprung-Associated Enterocolitis
Pages 209-223
Diagnosis of Hirschsprung Disease and Allied Disorders
Pages 225-231
Hirschsprung’s Disease and Anorectal Manometry
Pages 233-248
Rectal Biopsy for the Diagnosis of Hirschsprung’s Disease
Pages 249-254
Anatomic Pathology of Hirschsprung Disease
Pages 255-281
Total Colonic Aganglionosis and Very-Long-Segment Hirschsprung’s Disease
Pages 283-296
Hirschsprung’s Disease in Adolescents and Adults
Pages 297-303
Variants of Hirschsprung’s Disease
Pages 305-322
Megacystis Microcolon Intestinal Hypoperistalsis Syndrome
Pages 323-330
Degenerative Hollow Visceral Myopathy Mimicking Hirschsprung’s Disease
Pages 331-344
Transanal Pull-Through With or Without Laparoscopic Assistance for Rectosigmoid Hirschsprung’s Disease
Pages 345-355
Laparoscopically Assisted Pull-Through Operation for Hirschsprung’s Disease
Pages 357-371
Redo Pull Through Operation for Hirschsprung Disease
Pages 373-382
Early and Late Complications Following Pull-Through Operation for Hirschsprung’s Disease
Pages 383-401
Morphological Basis of Persistent Bowel Problems Following a Properly Performed Pull-Through Operation for Hirschsprung’s Disease
Pages 403-413
Bowel Management for the Treatment of Chronic Constipation and Soiling in Patients Operated for Hirschsprung’s Disease
Pages 415-420
Hirschsprung’s Disease and Inflammatory Bowel Disease
Pages 421-425
Intestinal Transplantation for Total Intestinal Aganglionosis
Pages 427-438
Urological and Sexual Outcomes in Patients with Hirschsprung’s Disease
Pages 439-449
Long-Term Outcome and Quality of Life After Treatment of Hirschsprung’s Disease
Pages 451-462
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