Titolo: Hepatocellular Carcinoma

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Gastroenterologia ed Epatologia

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Hepatocellular Carcinoma

Diagnosis and Treatment

Editore

Springer

Anno

2016

Pagine

596

ISBN

9783319342122

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

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• Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. However, the increasing numbers of chronic HCC carriers in the U.S. and subsequent increased incidences of HCC seen in most large medical centers means that it is no longer an uncommon disease for gastroenterologists or oncologists to encounter and its incidence and epidemiology are changing. During this exciting time in the field of HCC basic science and clinical management, many changes are simultaneously occurring at multiple levels of our understanding and management of the disease. Suddenly, there are several new choices of therapy to offer patients. Hepatocellular Carcinoma, 3rd edition addresses this fast-changing disease and gives the reader a clearer understanding of the many mechanisms involved in carcinogenesis of the liver. This comprehensive and detailed review of how to diagnose and treat hepatocellular carcinoma is written by international leaders in the field, covering both clinical treatment choices and the basic science underlying HCC development. Updated and enhanced from the last edition in 2009, Hepatocellular Carcinoma, 3rd edition features 12 new chapters including discussion of molecular markers, molecular hepatocarcinogenesis, microenvironment, heterogeneity, the new and exciting contributions of immunotherapy, and updates on the major effective hepatitis therapies that will transform HCC incidence and perhaps also the therapy. This cutting-edge text is a vital resource and must-have for today’s hepatologists and medical and surgical oncologists.

"This is a well written text and should be a good reference book for those who see patients with HCC.." - Practical Gastroenterology

"...a useful tool for both physicians and surgeons with a specific interest in the management of patients with HCC." - Digestive and Liver Disease

Epidemiology of Hepatocellular Carcinoma

White, Donna L. (et al.)

Pages 3-24
Environmental Carcinogens and Risk for Human Liver Cancer

Groopman, John D.

Pages 25-41
Molecular Mechanisms of Hepatocellular Carcinoma

Alotaibi, Hani (et al.)

Pages 43-63
Chemically-Induced Hepatocarcinogenesis

Dragan, Yvonne P.

Pages 65-92
Molecular Profiling of Human Hepatocellular Carcinoma

Budhu, Anuradha (et al.)

Pages 93-112

Genomic Signatures of Risk Factors and Molecular Identification of HCC Subtypes

Nault, Jean-Charles (et al.)

Pages 113-119
MicroRNAs and Hepatocellular Carcinoma

Cavallini, Aldo

Pages 121-137
Nontumor Prognostic Factors in Hepatocellular Carcinoma

Goossens, Nicolas (et al.)

Pages 139-147
Gut Microbiota and HCC

Loosen, Sven H. (et al.)

Pages 149-155
Hepatocellular Carcinoma as a Paradigm for a Systemic Evolutionary Approach to Cancer

Mazzocca, Antonio (et al.)

Pages 157-161
HCC and Its Microenvironment

Carr, Brian I.

Pages 163-166
Circulating Tumor Cells (Liquid Tumor Biopsy) in Hepatocellular Carcinoma: Biology, Methodologies, and Clinical Implications

Yin, Zhengfeng

Pages 167-197
Role of the Immune System in Hepatocellular Carcinoma: Implications for Existing and Novel Therapies

Flecken, Tobias (et al.)

Pages 199-210
Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma

Denisov, Evgeny V. (et al.)

Pages 211-228
Systemic Inflammation: A New Prognostic Domain and Source of Therapeutic Targets in Hepatocellular Carcinoma

Pinato, David J. (et al.)

Pages 229-241
Hepatocellular Carcinoma Associated with Hepatitis B Virus

Houri, Inbal (et al.)

Pages 243-259
Hepatitis C and Hepatocellular Carcinoma

Masuzaki, Ryota (et al.)

Pages 261-273
Obesity, NASH, and HCC

Robertson, Chadia L. (et al.)

Pages 275-286
Metabolic Disease and Hepatocellular Carcinoma

Thiel, David H. (et al.)

Pages 287-301
Aspects of Hepatocellular Tumor Pathology

Nalesnik, Michael A.

Pages 305-329
Protein Biomarkers in the Management of Hepatocellular Carcinoma: Novel Combinatory Approaches

Johnson, Philip (et al.)

Pages 331-338
Surveillance for Hepatocellular Carcinoma

Della Corte, Cristina (et al.)

Pages 339-354
Use of Imaging Techniques to Screen Hepatocellular Carcinoma

Goshima, Satoshi

Pages 355-365
Ultrasound of Hepatocellular Carcinoma: The Important Contribution of Contrast Enhancement

Kim, Tae Kyoung (et al.)

Pages 367-390
MRI for Detection and Evaluation of Hepatocellular Carcinoma

Patel, Anuj (et al.)

Pages 391-397

Computed Tomography of HCC

Agnello, Francesco (et al.)

Pages 399-408
Clinical Features and Clinician’s Diagnostic Approach to Hepatocellular Carcinoma

Thurm, Tamar (et al.)

Pages 409-423
Current HCC Staging Systems: Their Uses and Limitations

Tokumitsu, Yukio (et al.)

Pages 425-442
Percutaneous Ethanol Injection

Livraghi, Tito (et al.)

Pages 445-452
Thermal Ablative Treatments for Hepatocellular Carcinoma

Facciorusso, Antonio (et al.)

Pages 453-466
Resection of Hepatocellular Carcinoma

Lubezky, Nir (et al.)

Pages 467-475
Liver Transplantation for Hepatocellular Carcinoma

Györi, Georg (et al.)

Pages 477-488
Medical Therapy of HCC

Carr, Brian I. (et al.)

Pages 489-512
Targeted Therapies for Hepatocellular Carcinoma

Kralian, Susan (et al.)

Pages 513-529
Radiation Therapy for Hepatocellular Carcinoma

Kennedy, Andrew S.

Pages 531-546
Psychosocial Issues in Hepatocellular Carcinoma

Steel, Jennifer L. (et al.)

Pages 547-577
Bringing It All Together

Carr, Brian I.

Pages 579-584