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Epidemiology and Aetiology of Head and Neck Cancers
Pages 1-57
This second edition provides a comprehensive view of consolidated and innovative concepts, in terms of both diagnosis and treatment. Written by leading international physicians and investigators, this book emphasizes the necessity of combining local and systemic treatments to achieve the objective of yielding higher cure rates and lower toxicities. Heavily updated from the previous edition, it highlights new surgery and radiotherapy techniques, disease awareness, patient quality of life, and comprehensive management.
Head-and-neck cancers are a complex clinical entity and their response to treatment is also known to vary markedly in function of host-related factors. Notwithstanding the impressive progresses observed in the field of imaging, head and neck cancers are often diagnosed at a late stage and the presence of locally advanced disease in a significant number of patients implies the use of aggressive treatments in order to both ensure local disease control and reduce distant metastasis risks.
In comparison with the first edition, Head and Neck Cancer, Second Edition provides a detailed update of innovative concepts in chemo- and bio-radiation, viral infection impact on tumor growth and response to treatment, and impact of tumor- and host-related factors on treatment outcome.
Epidemiology and Aetiology of Head and Neck Cancers
Pages 1-57
Head and Neck Cancer Prevention
Pages 59-76
Cellular and Molecular Pathology of Head and Neck Tumors
Pages 77-99
Oncogenomics/Proteomics of Head and Neck Cancers
Pages 101-114
Genetics and Epigenetics of Head and Neck Cancer
Pages 115-132
Immunology of Head and Neck Cancer
Pages 133-148
Biomarkers in Head and Neck Cancer
Pages 149-162
HPV and EBV in Head and Neck Cancer
Pages 163-179
Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCC
Pages 181-203
Preclinical Models of Head and Neck Squamous Cell Carcinoma
Pages 205-213
Translational Research in Head and Neck Oncology
Pages 215-227
Hypoxia in Head and Neck Cancers: Clinical Relevance and Treatment
Pages 229-242
Imaging of Head and Neck Cancers
Pages 243-264
Ultrasound Investigations in Head and Neck Cancer Patients
Pages 265-278
Sentinel Node Biopsy
Pages 279-299
Intensity-Modulated Radiation Therapy for Head and Neck Cancer
Pages 301-315
Stereotactic Radiotherapy in Head and Neck Cancer Patients
Pages 317-324
Proton Beam Therapy for Head and Neck Cancer
Pages 325-336
Principles of Systemic Chemotherapy for Squamous Cell Head and Neck Cancer
Pages 337-348
Molecular Targeted Therapies in Head and Neck Cancer
Pages 349-372
Laser Endoscopic Treatment
Pages 373-385
Transoral Robotic Surgery in Head and Neck Cancer
Pages 387-390
Multidisciplinary Management of Skull Base and Superstructure Tumors
Pages 391-403
Multidisciplinary Management of Oral Cavity and Maxillary Sinus Cancers
Pages 405-428
Oral Oncology
Pages 429-443
Management of Nasopharyngeal Carcinoma
Pages 445-473
Multidisciplinary Management of Oropharynx Carcinomas
Pages 475-510
Multidisciplinary Management of Hypopharyngeal Carcinoma
Pages 511-537
Cancers of the Larynx: Tis, T1, T2 Evaluation and Management
Pages 539-553
Diagnosis and Multidisciplinary Treatment of Laryngeal Cancers
Pages 555-567
Programs of Organ and Function Preservation
Pages 569-574
Principles and New Approaches in Surgical Reconstruction
Pages 575-589
Multidisciplinary Treatment of the Neck
Pages 591-606
Postoperative Management of High-Risk Resectable Head and Neck Cancer
Pages 607-615
Multidisciplinary Approach of Unresectable Head and Neck Cancer
Pages 617-624
Management of Salivary Gland Cancer
Pages 625-640
Primary Mucosal Melanomas of the Head and Neck
Pages 641-656
Head and Neck Cutaneous Melanoma
Pages 657-663
Cervical Lymph Node Metastases of Squamous Cell Carcinoma from an Unknown Primary Site
Pages 665-672
The Management of Thyroid and Parathyroid Cancer
Pages 673-692
Head and Neck Paragangliomas
Pages 693-709
Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
Pages 711-729
Phase I Study Methodology in Head and Neck Oncology
Pages 731-742
Treatment of the Elderly Head and Neck Cancer Patient
Pages 743-751
Normal Tissue Complications and Protection in Head and Neck Cancer Patients
Pages 753-767
Advances in Management of Complications for Head and Neck Cancer Therapy
Pages 769-782
Rehabilitation of Heavily Treated Head and Neck Cancer Patients
Pages 783-798
Salvage Therapy in Head and Neck Cancer Patients
Pages 799-808
Quality of Life in Head and Neck Cancer Patients
Pages 809-820
Psycho-oncologic Aspects of Head and Neck Cancer Patients
Pages 821-826
Advances in Nanomedicine for Head and Neck Cancer
Pages 827-844
Head and Neck Quality Assurance 2014
Pages 845-859
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