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Historical Perspective and Current Trends in Haploidentical Transplantation
Pages 1-11
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Haploidentical Transplantation
Concepts & Clinical Application
Ciurea, Handgretinger
Editore
Springer
Anno
2018
Pagine
337
ISBN
9783319543093
110,00 €
DA SCONTARE
In this book, world-renowned experts in the field express well-reasoned opinions on a range of issues and controversies relating to haploidentical transplantation with the aim of providing practicing hematologists with clinically relevant and readily applicable information. Among the areas covered are graft manipulation and methods to control T-cell alloreactivity, the nature of the ideal graft and donor, haploidentical transplantation in pediatric and adult patients with malignant and nonmalignant diseases, immunologic reconstitution following transplantation, complications, and the prevention and treatment of relapse post transplantation. Attention is drawn to the implications of high-impact clinical trials whenever such trials are available. The readily intelligible text is complemented by numerous helpful tables, algorithms, and figures. The book will provide practical support for hematologists and transplant physicians as they attempt to provide optimal care in this exciting but increasingly complex medical specialty.
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Toward Safer CD34+ Megadose T-Cell-Depleted Transplants Following Reduced Intensity and Nonmyeloablative Conditioning Regimens
Pages 15-28
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Selective Allo-depletion: TcRαβ and CD19+ T-Cell Depletion
Pages 29-42
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Adoptive Immunotherapy with Regulatory and Conventional T-cells in Haploidentical T-cell Depleted Transplantation Protects from GvHD and Exerts GvL Effect
Pages 43-54
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Haploidentical Transplantation Using Unmanipulated G-CSF-Primed Blood and Marrow as Allografts: Clinical Data and Challenges
Pages 55-79
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Photodepletion to Promote Immune Reconstitution Without Graft-Versus-Host Disease After HLA-Haploidentical Transplantation
Pages 81-88
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Post-transplant Cyclophosphamide in Haploidentical Transplantation
Pages 89-107
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Graft Source: Marrow or Peripheral Blood with Posttransplant Cyclophosphamide—What Matters?
Pages 111-125
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Anti-HLA Antibodies: Assessment and Mitigating Strategies
Pages 127-143
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Haploidentical Transplants and NK Cell Alloreactivity
Pages 145-157
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Myeloablative Versus Nonmyeloablative Conditioning Regimen in Haploidentical Transplantation: Does It Matter and How Best to Select Between the Two?
Pages 159-171
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Haploidentical Transplants for Nonmalignant Diseases in Children
Pages 175-194
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Haploidentical Hematopoietic Cell Transplantation in Children with Neoplastic Disorders
Pages 195-215
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Haploidentical Transplants: Nonmalignant Diseases in Adults
Pages 219-229
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Haploidentical Transplants for Acute Myeloid Leukemia in Adults
Pages 231-243
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Haploidentical Hematopoietic Cell Transplantation in Lymphomas
Pages 245-260
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Haploidentical Transplants for Myeloproliferative Neoplasms
Pages 261-269
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Haploidentical Transplants: Immune Reconstitution With and Without Augmentation Strategies
Pages 271-289
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Prevention and Treatment of Relapse After HLA-Haploidentical Hematopoietic Cell Transplantation
Pages 291-306
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Unique Complications and Limitations of Haploidentical Hematopoietic Cell Transplant
Pages 307-323
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Future Prospects: Haploidentical Transplantation
Pages 325-337
