TABLE OF CONTENTS

About the Editors

List of Contributors

Preface

Acknowledgments

Part 1: The Aging Brain in Neurology

1 The Biology of Aging: Implications for Diseases of Aging and Health Care in the Twenty-First Century
Douglas F. Watt

2 Functional Changes Associated with the Aging Nervous System
Julie A. Schneider and Chunhui Yang

Part 2: Assessment of the Geriatric Neurology Patient

3 Approach to the Geriatric Neurology Patient: The Neurologic Examination
Marwan N. Sabbagh and Anil K. Nair

4 Assessment of Cognitive Status in Geriatric Neurology

4.1 Mental Status Examination in the Geriatric Neurology Patient
Papan Thaipisuttikul and James E. Galvin

4.2 Neuropsychology in Geriatric Neurology
Donald J. Connor and Marc A. Norman

5 Cognitive Reserve and the Aging Brain
Adrienne M. Tucker and Yaakov Stern

6 Gait Disorders in the Graying Population
Joe Verghese and Jessica Zwerling

7 Imaging of the Geriatric Brain

7.1 Structural Neuroimaging in Degenerative Dementias
Liana G. Apostolova

7.2 Functional Imaging in Dementia
Adam S. Fleisher and Alexander Drzezga

7.3 Amyloid Imaging
Anil K. Nair and Marwan N. Sabbagh

8 Clinical Laboratory Investigations in Geriatric Neurology
Geoffrey S. Baird and Thomas J. Montine

Part 3: Neurologic Conditions in the Elderly

9 Cognitive Impairment and the Dementias

9.1 Mild Cognitive Impairment
Ranjan Duara, Miriam Jocelyn Rodriguez, and David A. Loewenstein

9.2 Alzheimer's Disease
Martin R. Farlow

9.3 Dementia with Lewy Bodies
Clive Ballard

9.4 Vascular Cognitive Impairment
Helena C. Chui and Freddi Segal-Gidan

9.5 Frontotemporal Dementia
David Perry and Howard Rosen

9.6 Primary Progressive Aphasia
Maya L. Henry, Stephen M. Wilson, and Steven Z. Rapcsak

9.7 Prion Diseases
Michael D. Geschwind and Katherine Wong

9.8 Normal Pressure Hydrocephalus
Norman R. Relkin

10 Depression in the Elderly: Interactions with Aging, Stress, Chronic Pain, Inflammation, and Neurodegenerative Disorders
Douglas F. Watt

11 Cerebrovascular Diseases in Geriatrics
Patrick Lyden, Khalil Amir and Ilana Tidus

12 Movement Disorders

12.1 Parkinson's Disease
Robert Fekete and Joseph Jankovic

12.2 Essential Tremor and Other Tremor Disorders
Holly Shill

12.3 Progressive Supranuclear Palsy
Virgilio Gerald H. Evidente

12.4 Corticobasal Degeneration
Katrina Gwinn

13 Sleep Disorders
Sanford Auerbach

14 Autonomic Dysfunction and Syncope
Rohit R. Das

15 Geriatric Epilepsy
David V. Lardizabal

16 Vertigo and Dizziness in the Elderly
Terry D. Fife and Salih Demirhan

17 Disorders of the Special Senses in the Elderly
Douglas J. Lanska

18 Nervous System Infections
Ronald Ellis, David Croteau, and Suzi Hong

19 Delirium
Alan Lerner, Stefani Parrisbalogun, and Joseph Locala

20 Headache in the Elderly
Brian McGeeney

21 Neuromuscular Disorders
Heber Varela and Clifton Gooch

Part 4: Therapeutics for the Geriatric Neurology Patient

22 Neurosurgical Care of the Geriatric Patient
David Fusco, Rasha Germain, and Peter Nakaji

23 Treatment of Dementia

23.1 Evidence-Based Pharmacologic Treatment of Dementia
Jasmeet Singh, Marwan N. Sabbagh, and Anil K. Nair

23.2 Immunotherapy for Alzheimer's Disease
Michael Grundman, Gene G. Kinney, Eric Yuen, and Ronald Black

24 Geriatric Psychopharmacology
Sandra A. Jacobson

25 Nonpharmacologic Treatment of Behavioral Problems in Persons with Dementia
Gary A. Martin and John Ranseen

26 Expressive Art Therapies in Geriatric Neurology
Daniel C. Potts, Bruce L. Miller, Carol A. Prickett, Andrea M. Cevasco, and Angel C. Duncan

Part 5: Important Management Issues Beyond Therapeutics in the Geriatric Neurology Patient

27 Dietary Factors in Geriatric Neurology
Yian Gu and Nikolaos Scarmeas

28 Exercising the Brain: Nonpharmacologic Interventions for Cognitive Decline Associated with Aging and Dementia
Brenna A. Cholerton, Jeannine Skinner, and Laura D. Baker

29 Driving Impairment in Older Adults
Anne D. Halli-Tierney and Brian R. Ott

30 Elder Abuse and Mistreatment
Elliott Schulman, Ashley Roque, and Anna Hohler

31 Advocacy in Geriatric Neurology
Glenn Finney and Anil K. Nair

Index