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Libreria medica internazionale
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LIBRERIA STUDIUM
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Genetics of Rare Autoimmune Diseases
Martin, Carmona,
Editore
Springer
Anno
2019
Pagine
240
ISBN
9783030039332
110,00 €

DA SCONTARE

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

The main aim of this volume is to provide an updated overview of the genetic basis of a group of complex disorders that are considered rare individually, but show a relatively high prevalence on the whole in developed countries: the rare autoimmune diseases. These are chronic disorders that involve long and expensive treatments with considerable side effects that may dramatically reduce the quality of life of affected people. Therefore, shedding light into their pathologic mechanisms is a major concern given their growing social and economic awareness and impact.

General sections include different chapters on single entities as systemic lupus and sclerosis, Behçet’s disease, Sjogren’s syndrome and polymiositis, and sections devoted to autoimmune vasculitis, hepatic autoimmune conditions, as well as those affecting the nervous system, and a concluding chapter in which the shared predisposition amongst all diseases is discussed. All the chapters are given a homogeneous scheme in which the authors explain the clinical singularities of every disease and report the recent breakthrough discoveries related to them, giving a critical interpretation and suggesting future perspectives. All contributors are renowned researchers with high expertise in each disease. Due to the exponential increase in our understanding of the genetic causes of these complex diseases, a major advance in biomedical discovery is taking place. However, most of the achievements in this field are very recent and there is a lack of bibliography gathering them together. This book is thus filling a gap and will prove a useful companion to clinicians in the first place (internists, rheumatologists, clinical immunologists, and hematologists) but also to basic and applied researchers.

  • Systemic Lupus Erythematosus

    Vester, Susan K. (et al.)

    Pages 1-17

  • Systemic Sclerosis

    López-Isac, Elena (et al.)

    Pages 19-35

  • Behçet’s Disease

    Ortiz-Fernández, Lourdes (et al.)

    Pages 37-51

  • Sjögren’s Syndrome

    Pottier, Laëtitia (et al.)

    Pages 53-94

  • Polymyositis/Dermatomyositis

    Márquez, Ana (et al.)

    Pages 95-110

  • ANCA-Associated Vasculitis

    Bonatti, Francesco (et al.)

    Pages 111-128

  • Giant Cell Arteritis

    Carmona, Francisco David (et al.)

    Pages 129-149

  • Takayasu Arteritis

    Gensterblum, Elizabeth (et al.)

    Pages 151-162

  • Primary Biliary Cirrhosis, Primary Sclerosing Cholangitis, and Autoimmune Hepatitis

    González-Serna, David (et al.)

    Pages 163-182

  • Genetics of Multiple Sclerosis

    Alcina, Antonio (et al.)

    Pages 183-202

  • Autoimmune Myasthenia Gravis

    Saruhan-Direskeneli, Güher (et al.)

    Pages 203-219

  • Common Genetic Component in Autoimmunity

    Orozco, Gisela (et al.)

    Pages 221-236

 

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