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Epidemiology and Etiology of Ovarian Cancer
Pages 1-13
This volume presents the latest advances and the current status of our understanding regarding ovarian cancer, addressing both the basic and clinical aspects of the disease.
In terms of basic medicine, the WHO Classification of Tumors of Female Reproductive Organs was revised in 2014, and that version addresses several new concepts and histopathological classifications not previously included. One of the most revolutionary breakthroughs concerns the genesis of epithelial ovarian tumors, shifting the focus from the ovarian surface epithelium to serous tubal intraepithelial carcinomas.
Clinically, the mortality rate of epithelial ovarian cancer has gradually increased over the past few decades, making it essential to pursue multidisciplinary treatment and apply novel techniques such as neoadjuvant chemotherapy in daily clinical practice. The primary clinical task is the effective treatment of recurrent ovarian cancer with early palliative medicine. Fertility-sparing surgery may also be pursued depending on histologic subtypes, stage, extent of disease, and preexisting ovarian reserve with the concept of oncofertility.
On the basis of the considerations described above, each expert author elucidates the science of ovarian cancer in detail, thus providing a collection that will benefit young medical oncologists and seasoned gynecologists and obstetricians alike.
Epidemiology and Etiology of Ovarian Cancer
Pages 1-13
Hereditary Ovarian Cancer
Pages 15-35
Morphological and Molecular Pathogenesis of Epithelial Ovarian Tumors
Pages 37-56
Screening and Prevention of Ovarian Cancer
Pages 57-81
Pathology of Epithelial Ovarian Tumors
Pages 83-113
Pathology of Non-epithelial Ovarian Tumors
Pages 115-141
Ovarian Cancer Genome and Molecular Experimental Sciences
Pages 143-154
Strategies for the Management of Epithelial Ovarian Cancer
Pages 155-164
Strategies for the Management of Epithelial Ovarian Borderline Tumors
Pages 165-171
Strategies for the Management of Non-epithelial Ovarian Tumors
Pages 173-190
Primary Surgical Treatment of Epithelial Ovarian Cancer
Pages 191-205
Primary Chemotherapy and Targeted Molecular Therapy of Epithelial Ovarian Cancer
Pages 207-224
Immunology and Immunotherapy in Ovarian Cancer
Pages 225-242
Treatment of Recurrent Epithelial Ovarian Cancer
Pages 243-265
Management of Ovarian Cancer in Adolescents and Young Adults
Pages 267-279
Management of Ovarian Cancer in the Elderly Population
Pages 281-303
Palliative Medicine in the Management of Ovarian Cancer
Pages 305-314
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