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We have entered a new era in breast cancer management where disease is "small" and more likely to be confined to the breast and regional nodes. Some of these tumours will have minimal proclivity for hematogenous dissemination and formation of micrometastases at an early stage in the neoplastic process. By contrast, some patients have micrometastatic diseases which can remain dormant and be activated many years after the diagnosis.
Early Breast Cancer: From Screening to Multidisciplinary Management discusses the principles and practice of breast cancer management within the context of the multidisciplinary team working with respect to both screen-detected and symptomatic disease. It also includes coverage of key areas of contemporary interest and potential controversy.
The book provides readers with sound understanding and critical insight into many aspects of the disease from epidemiology, genetics, and screening to pathology, diagnosis, treatment, and prevention. This latest edition continues the general ethos of the second edition with an emphasis on breast cancer screening and continued development of the multidisciplinary team.
	RISK ASSESSMENT AND PREVENTION OF BREAST CANCER
	An Introduction to Screening for Breast Cancer, Linda J. Pointon, Sue K. Down
	Mammographic Density as an Early Indicator of Breast Cancer, Jajini Susan Varghese
	Genetic Predisposition and Breast Screening, D. Gareth Evans
	Application of New Genomic Technologies to Breast Cancer Risk Assessment, Mark Robson
	Endocrine Prevention of Breast Cancer, Russell E. McDaniel, V. Craig Jordan
	
	BREAST CANCER SCREENING
	The Biological Basis for Breast Cancer Screening and Its Relevance to Treatment, John R. Benson
	Interval Cancers, Anthony J. Maxwell
	Survival Advantage of Screen-Detected Cancer over Stage-Matched Symptomatic Cancer, Gordon C. Wishart
	Mammography Screening for Women under Age 50, Ismail Jatoi, Pranjali V. Gadgil
	Mammographic Screening in Women Aged 50 Years and Above, Chris I. Flowers
	The Organization of Breast Screening, Julietta Patnick
	Quality Assurance and Evaluation of Outcomes in the NHS Breast Screening Programme, Gill Lawrence
	
	BREAST CANCER—DIAGNOSTIC EVALUATION
	Clinical Assessment of Symptomatic Patients, J. Mathew, K.L. Cheung
	Film Reading and Recall from Screening Mammography, Sabrina Rajan, Susan J. Barter, Erika Denton
	Radiology of the Normal Breast and Differential Diagnosis of Benign Breast Lesions, Jessica Kuehn-Hajder, Claudia Engeler, Tim Emory
	Breast Masses, A. Robin M. Wilson
	Asymmetry and Architectural Distortion, Michael J. Michell
	The Radial Scar, Sabrina Rajan, Pauline J. Carder
	Role of Ultrasound in the Diagnosis of Breast Cancer, Hannah Gay, Steven D. Allen
	The Role of MRI in Preoperative Evaluation and Postoperative Follow-Up of Breast Cancer Patients, Richard J. Bleicher
	PET Scanning and Breast Cancer Management, Rebecca Wight, Patrick Borgen
	
	TISSUE DIAGNOSIS
	Core Biopsy of Breast Lesions, Kathryn Taylor, Peter D. Britton
	Vacuum-Assisted Breast Biopsy, Thomas Conner, William The
	Preoperative Localization of Impalpable Breast Lesions, Sabrina Rajan, Erika Denton, Susan J. Barter
	
	BREAST PATHOLOGY
	The Normal Breast and Benign Breast Lesions, Baljit Singh
	Histological Risk Factors, Prognostic Indicators, and Staging, Emad A. Rakha, Sarah Pinder, Ian O. Ellis
	Premalignant and Borderline Lesions: Ductal and Lobular Carcinoma In Situ, Clive A. Wells, Evdokia Arkoumani
	Invasive Breast Carcinoma, Elena Provenzano
	Molecular Investigation of Breast Cancer, Paul M. Wilkerson, J.S. Reis-Filho
	
	MULTIDISCIPLINARY MANAGEMENT OF BREAST CANCER
	The Role of Multidisciplinary Teams in Breast Cancer Management, Cath Taylor, Amanda Shewbridge, Massimiliano Cariati, Anand Purushotham
	Shared Decision-Making for Breast Cancer Patients, Catharine F. Clay, Alice O. Andrews, Dale Collins Vidal
	The Evolving Role of the Breast Care Nurse in the Management of Patients with Early Breast Cancer, Rebecca Llewellyn-Bennett, Jane Barker, Zoë Ellen Winters
	Informed Consent in the Management and Research of Breast Cancer, Hazel Thornton
	
	SURGICAL MANAGEMENT OF EARLY-STAGE BREAST CANCER
	Ductal Carcinoma In Situ of the Breast, Melvin J. Silverstein, Michael D. Lagios
	Principles of Surgical Treatment of Invasive Breast Cancer, Starr Koslow, Rache M. Simmons
	The Optimum Resection Margin in Breast Conservation Surgery, Lisa Newman, Jessica Bensenhaver
	Skin-Sparing Forms of Mastectomy, Gerald Gui
	Locoregional Recurrence of Breast Cancer, John R. Benson, Katy Teo
	Management of the Axilla I, John R. Benson, Mattia Intra
	Management of the Axilla II, Laura Dominici, Mehra Golshan
	
	TECHNIQUES FOR BREAST IRRADIATION
	Radiation Therapy Following Breast Conserving Surgery or Mastectomy, Ian Kunkler
	Partial Breast Irradiation, Charlotte Coles, Mukesh Mukesh, Martin Keisch
	Targeted Intraoperative Radiotherapy for Breast Cancer: Not All Cancers in the Breast Will Grow, Jayant S. Vaidya, John R. Benson, Jeffrey S. Tobias
	
	SYSTEMIC THERAPIES FOR EARLY-STAGE BREAST CANCER
	Systemic Hormonal Therapies for Early-Stage Breast Cancer, Stephen R.D. Johnston
	Adjuvant Chemotherapy and Biological Therapies for Early-Stage Breast Cancer, Sausan Abouharb, Francisco J. Esteva
	Primary Systemic Therapy in Breast Cancer, Lisardo Ugidos, Andreas Makris, Jenny C. Chang
	
	EARLY-STAGE BREAST CANCER—SPECIAL CIRCUMSTANCES
	Breast Cancer in the Rlderly, R.C.F. Leonard, G.A. Thomas
	Breast Cancer and Pregnancy, Christobel Saunders, Angela Ives
	Male Breast Cancer, Maisam Z. Fazel, Vassilis Pitsinis
	Trends in the Use of Contralateral Prophylactic Mastectomy, Todd M. Tuttle
	The Principles of Breast Reconstructive Surgery, Animesh J.K. Patel, Rosanna C. Ching, John R. Benson, Charles M. Malata
	Index
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