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Taxonomy of Medication Adherence: Recent Developments
Pages 1-8
This book provides a critical and comprehensive review of the methodologies available for measuring drug adherence in clinical practice, including those relying on emerging technologies. The authors discuss the risk factors of non-adherence and shed light on how to identify patients at risk of poor adherence. Drug therapies in chronic diseases rely heavily on the patient's adherence, since drugs that are not taken are ineffective and leave the patient at high risk of developing clinical complications. Given the absence of new drugs for the treatment of hypertension, drug adherence is particularly important in these patients to improve blood pressure control. The book further investigates a new aspect, namely the importance of drug adherence in clinical trials and studies and draws attention to the limits of developing drugs without significant information on drug adherence. Several chapters are dedicated to the importance of adherence in specific forms of hypertension, such as resistant hypertension, dyslipidemia and hypertension associated with cardiovascular risk. As experts confronted with drug adherence in their daily practice, the authors analyse the real effectiveness of several interventions aimed at improving drug adherence and put particular emphasis on the importance of an interdisciplinary approach involving nurses and pharmacists. The volume also includes a careful analysis of the health and economic impact of poor adherence. The book is aimed at physicians, pharmacists, students and all health professionals dealing not only with hypertension or dyslipidemia, but also with chronic asymptomatic diseases such as diabetes, HIV or chronic respiratory diseases.
Taxonomy of Medication Adherence: Recent Developments
Pages 1-8
Qualitative Assessments of Adherence
Pages 11-19
Electronic Monitoring of Medication Adherence: From Dose-Counting to Dose-Clocking
Pages 21-27
Measurements of Antihypertensive Medications in Blood and Urine
Pages 29-41
Adherence to Antihypertensive and Cardiovascular Preventive Treatment: The Contribution of the Lombardy Database
Pages 43-56
Directly Observed Therapy in Hypertension (DOT-HTN)
Pages 57-85
Digital Medicines to Measure Drug Ingestion Adherence
Pages 87-97
Ethical Aspects of Measuring Adherence to Antihypertensive Treatment
Pages 99-104
Determinants and Barriers to Adherence in Hypertension
Pages 107-122
Beliefs and Adherence in Hypertension and Cardiovascular Protection
Pages 123-141
Impact of Drug Adherence in Clinical Trials
Pages 145-151
The Impact of Antihypertensive Drugs on Adherence
Pages 153-172
Medication Persistence in Hypertension in General Practice
Pages 173-184
Drug Adherence in Resistant Hypertension
Pages 185-197
Drug Adherence with Cardiovascular Medicines: Statins and Aspirin
Pages 199-217
Which Interventions Are Useful?
Pages 219-223
Use of Fixed-Dose Combinations in Hypertension and Cardiovascular Disease Prevention
Pages 225-235
Nurse Led Interventions in Hypertension
Pages 237-252
Role of the Pharmacist in Supporting Adherence
Pages 253-269
Integrated Approaches to Support Medication Adherence: The Case of Hypertension
Pages 271-281
Use of Apps to Improve Drug Adherence in Hypertensive Patients
Pages 283-293
Global Clinical Consequences of Poor Adherence
Pages 297-314
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