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Diagnostic Cytology
Pranab Dey
Editore
Jaypee
Anno
2014
Pagine
544
ISBN
9789351520665
140,00 €
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Cytology is the study of cells; diagnostic cytology involves studying cells to identify diseases. The process is commonly used to detect cancer, but is also helps in the diagnosis of certain infectious diseases and other inflammatory conditions.

This book is a comprehensive guide to diagnostic cytology. Divided into four sections, the book begins with an introduction to general cytology, providing an overview of cells, cell cycles and cell death. The following sections discuss clinical cytology, examining cells in specific areas of the body, and laboratory techniques for studying them.

The final part is dedicated to fine needle aspiration cytology (FNAC), a popular and effective technique for quick tissue diagnosis. This section describes the use of FNAC in all different areas of the body.

 

Key points

  • Comprehensive guide to diagnostic cytology covering general cytology and more specific use of diagnosis techniques in different parts of the body
  • In depth coverage of laboratory techniques
  • Complete section dedicated to fine needle aspiration  cytology
  • Includes nearly 1000 clinical photographs, illustrations and tables

Author information

Pranab Dey MBBS MD MIAC FRCPATH
Professor, Department of Cytology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

 

CONTENTS

Section 1:

General Cytology

chapter

1

Cell

3

Eukaryotic versus Prokaryotic Cells

3

Cell Membrane

3

Cytoplasmic Organelles

9

Nucleus

15

Deoxyribonucleic Acid

19

c

hapter

2

Cell Cycle and Cell Proliferation

24

Cell Cycle

24

Cell Cycle Control and Cancer

29

Cell Proliferation Markers

31

c

hapter

3

Cellular Reaction to Injury and Cell Death

35

Cellular Adaptation

35

Reversible Cell Injury

36

Irreversible Injury

37

Apoptosis or Type I Programmed Cell Death

37

Autophagy

41

Necrosis

43

Inflammation 44

c

hapter

4

Molecular Genetics: Basic Principles and Clinical

a

pplications

46

Chromosome

46

Molecular Cytogenetic Techniques

51

Prognosis of the Patient

54

c

hapter

5

n

eoplasm

57

Benign Neoplasm

57

Biological Characteristics of Malignant Tumor or Cancer

59

Hallmarks of Cancer

59

Cancer Stem Cells

63

Molecular Basis of Cancer

63

Clonal Evolution of Cancer

63

Oncogenes and Cancer

63

Functional Properties of Oncogene

65

Microribonucleic Acid and Cancer

66

Genomic Instability

67

Tumor-Suppressor Genes

69

Preneoplastic Lesions

72

Morphology of Cancer Cell

73

Overall Pattern

73

Cell and Cytoplasm

73

Nucleus

74

xii

diagnosti

C

Cytology

Mitosis

76

Other Nuclear Changes

77

Characterization of Type of Cancer Cell

78

Diagnostic Pitfalls of Malignancy

78

c

hapter

6

t

issue and Cell

o

rganization

81

Epithelial Tissue

81

Connective Tissue

83

Cluster of Differentiation

86

Section 2:

Cl

I

n

IC

al Cytolo

G

y (Exfol

I

at

I

v

E

C

ytolo

G

y)

c

hapter

7

Cervical Smear:

n

ormal Cytology, Bethesda System and

n

on-neoplastic

l

esions

89

Normal Anatomy, Histology and Cytology of Female Genital Tract

89

Normal Cells in Cervical Smear

92

Other Cells

95

Differential Diagnosis

96

Bethesda System of Reporting

96

Endocervical Cells

98

Organisms and Infection

99

Cytological Features of Reparative and Regenerative Changes

102

c

hapter

8

Cervical Carcinogenesis, Preneoplastic and

n

eoplastic Condition

106

Human Papilloma Virus and Cervical Carcinogenesis

106

Cervical Preneoplastic Lesions

108

Atypical Squamous Cells

114

Squamous Cell Carcinoma

115

Adenocarcinoma

117

Endometrial Adenocarcinoma

118

Extrauterine Carcinoma

122

c

hapter

9

Cervical Cancer Screening Program

124

Screening Principle

124

Parameters to Measure the Validity of Screening Tests

124

Types of Modalities for Cervical Cancer Screening

125

Essential Elements for Successful Cervical Cancer Screening

126

Recommendations of Cervical Cancer Screening

127

Problems of Screening in Developing Countries

127

Remedies to Avoid False Negative Cytology

128

c

hapter 10

Effusion Cytology

129

Anatomy and Histology of Body Cavities

129

Effusion

129

Specimen Collection and Processing

130

Benign Cell Population in Effusion

131

Effusion Due to Non-neoplastic Causes

134

Malignant Effusion

137

Ancillary Techniques

148

c

hapter 11

Urine Cytology

152

Anatomy

152

Histology

153

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