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Classification of Neuroendocrine Neoplasms
Pages 1-13
Based on the most novel approaches and cutting-edge clinical and scientific information regarding radionuclide imaging and therapies for neuroendocrine tumors, this clinical guidebook represents a unique collaborative effort between endocrinologists, nuclear physicians, oncologists, surgeons, physicists, radio-pharmacists and geneticists. It begins with the embryology, classification and molecular genetics of gastroenteropancreatic neuroendocrine tumors and carcinoids, chromaffin cell tumors, and MEN1- and MEN2-related tumors. Following a chapter on radiopharmaceuticals in neuroendocrine imaging, it turns to the physics and technology of current and cutting-edge radiology, including SPECT/CT and PET/CT and PET/MR. Discussing of radionuclide imaging covers the tumors mentioned above, as well as pulmonary and thymic neuroendocrine tumors and medullary thyroid carcinoma. A presentation of radionuclide therapies follows, including 131I-MIBG therapy, somatostatin receptor-based therapy, and alpha radionuclide therapy, as well as the role of nanoparticles.
Comprehensive and up-to-date, Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors will assist and guide physicians who encounter patients with these conditions, either from a diagnostic or therapeutic standpoint, and particularly emphasizes the current and emerging medical devices and imaging and therapeutic options.
Classification of Neuroendocrine Neoplasms
Pages 1-13
Molecular Genetics of Pheochromocytoma and Paraganglioma
Pages 15-45
Molecular Genetics of MEN1-Related Neuroendocrine Tumors
Pages 47-64
Molecular Genetics of MEN2-Related Neuroendocrine Tumours
Pages 65-81
Molecular Genetics of Neuroblastoma
Pages 83-125
Molecular Genetics of Gastroenteropancreatic Neuroendocrine Tumours
Pages 127-140
Current and Future Radiopharmaceuticals in Neuroendocrine Tumor Imaging
Pages 141-162
SPECT/CT, PET/CT and PET/MR Principles
Pages 163-200
Internal Dosimetry: Principles and Applications to NET
Pages 201-217
Principles and Application of Molecular Imaging for Personalized Medicine and Guiding Interventions in Neuroendocrine Tumors
Pages 219-238
Tumor Metabolism and Metabolomics of Pheochromocytomas and Paragangliomas
Pages 239-250
Radionuclide Imaging of Pheochromocytoma and Paraganglioma in the Era of Multi-omics
Pages 251-268
Radionuclide Imaging of Head and Neck Paragangliomas
Pages 269-294
Radionuclide Imaging of Chromaffin Cell Tumors
Pages 295-319
Radionuclide Imaging of Gastrointestinal Neuroendocrine Tumors
Pages 321-349
Radionuclide Imaging of Pancreatic Neuroendocrine Tumours
Pages 351-361
Radionuclide Imaging of Pulmonary and Thymic Neuroendocrine Tumors
Pages 363-379
Radionuclide Imaging of Medullary Thyroid Carcinoma
Pages 381-399
131I-Meta-Iodobenzylguanidine Therapy for Pheochromocytoma/Paraganglioma and Neuroblastoma
Pages 401-409
Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors
Pages 411-427
Alpha Radionuclide Therapy: Principles and Applications to NETs
Pages 429-445
Nanoparticles for Radionuclide Imaging and Therapy: Principles
Pages 447-471
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