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Clinical Classification
Pages 3-11
This book focuses on pulmonary arterial hypertension (PAH, Group 1) and chronic thromboembolic pulmonary hypertension (CTEPH, Group 4) among the various groups of pulmonary hypertension (PH) whose classification was updated into five major categories at the 5th World Symposium held in Nice, France, in 2013. Readers will find recent progress, methods, and up-to-date information on PH mechanisms, diagnostic images, and treatment in the management of PH.This volume, with contributions by leading researchers worldwide in the field , consists of five parts, starting with the fundamentals of PH, then pathophysiology and genetics, treatment, and right ventricular function
Clinical Classification
Pages 3-11
Diagnosis: Imaging
Pages 13-27
Pathogenic and Therapeutic Role of MicroRNA in Pulmonary Arterial Hypertension
Pages 31-54
Sex Hormones
Pages 55-65
Rho-Kinase as a Therapeutic Target for Pulmonary Hypertension
Pages 67-76
The Unique Property of the Pulmonary Artery Regarding the Smooth Muscle Effects of Proteinase-Activated Receptor 1: The Possible Contribution to the Pathogenesis of Pulmonary Hypertension
Pages 77-87
Animal Models with Pulmonary Hypertension
Pages 89-99
Human Pathology
Pages 101-113
Pathophysiology and Genetics: BMPR2
Pages 115-124
Prostacyclin
Pages 127-138
Targeting the NO-sGC-cGMP Pathway in Pulmonary Arterial Hypertension
Pages 139-151
Endothelin Receptor Antagonist
Pages 153-169
Lung Transplantation
Pages 171-182
Medical Therapy for Chronic Thromboembolic Pulmonary Hypertension
Pages 185-192
Balloon Pulmonary Angioplasty
Pages 193-202
Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension
Pages 203-214
Right Ventricular Function
Pages 217-236
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