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LIBRERIA STUDIUM
Libreria medica internazionale
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LIBRERIA STUDIUM
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Cytogenomics
Liehr
Editore
Elsevier
Anno
2021
Pagine
428
ISBN
9780128235799
155,00 €

DA SCONTARE

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.
Features:
  • Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies
  • Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease
  • Features chapter contributions from international leaders in the field

1. A Definition for Cytogenomics - also may be called Chromosomics

SECTION 1: Technical Aspects
2. Overview of yet available approaches used in Cytogenomics
3. Cytogenetics
4. Molecular Cytogenetics
5. Molecular Combing solutions to characterize replication kinetics and genome rearrangements
6. Molecular Karyotyping
7. Sequencing approaches
8. Optical mapping and karyo-mapping
9. Application of CRISPR/Cas9 to visualize defined genomic sequences in fixed chromosomes and nuclei
10. Approaches for studying epigenetic aspects of the human genome

SECTION 2: Current Cytogenomic Research
11. Chromoanagenesis phenomena and their formation mechanisms
12. Topologically associated domains and other gene regulatory elements
13. Multilayer organization of chromosomes
14. Nuclear architecture
15. Nuclear stability in early embryo. Chromosomal aberrations
16. Cytogenomic landscape of the human brain
17. Interchromosomal interactions with meaning for disease
18. Shaping of genome by long non-coding RNAs
19. Repetitive elements, heteromorphisms and copy number variants
20. Epigenetics

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