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Epidemiology and Genetic Basis of Fuchs Endothelial Corneal Dystrophy
Pages 1-16
This book provides state of the art information on modern minimally invasive lamellar transplant techniques for Fuchs endothelial dystrophy (FED), such as Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK). In addition to clear step-by-step descriptions of procedures, guidance is offered on donor tissue preparation, potential intra- and postoperative complications, and complication management. Future treatment options in the form of medical, cell-based approaches are also discussed. To complete the picture, relevant information is included on the pathophysiology, clinical features, and differential diagnosis of FED. This book will be of interest to all who wish to learn about the dramatic developments in corneal transplantation and medical treatment that are transforming the management of FED.
Epidemiology and Genetic Basis of Fuchs Endothelial Corneal Dystrophy
Pages 1-16
MicroRNAs in FECD: A New Therapeutic Option?
Pages 17-24
Clinical Phenotypes of Fuchs Endothelial Corneal Dystrophy (FECD), Disease Progression, Differential Diagnosis, and Medical Therapy
Pages 25-50
Optical and Anatomic Changes in Fuchs Endothelial Dystrophy Corneas
Pages 51-71
Evolution of Posterior Lamellar Keratoplasty: PK – DLEK – DSEK/DSAEK – DMEK – DMET
Pages 73-85
DMEK Graft Preparation: Eye Bank Perspective and Risk Factors for Preparation Failure
Pages 87-103
Donor-Tissue Splitting and Tissue Storage for DALK and DMEK Surgery
Pages 105-118
DSAEK and UT-DSAEK in FED: Step-by-Step Approach
Pages 119-132
DSAEK (Not Only) in Asian Eyes: What Glide to Use? Optimised Insertion Techniques
Pages 133-151
Intra- and Postoperative Complications and Their Management in DMEK (Including Re-DMEK)
Pages 153-164
DMEK: Step-by-Step Surgical Approach
Pages 165-187
Complications of Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) Surgery
Pages 189-204
Revision Surgical Options for Failed PK in FED
Pages 205-212
Long-Term Clear Graft Survival and Chronic Endothelial Cell Loss Following Posterior Lamellar Keratoplasty
Pages 213-226
Immune Reactions and Dry Eye After Posterior Lamellar Keratoplasty
Pages 227-235
Tissue Engineering of a Healthy Corneal Endothelium for FECD Patients
Pages 237-255
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