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Color Atlas of Differential Diagnosis in Dermatopathology
Loren E Clarke, Jennie T Clarke, Klaus F Helm
Editore
Jaypee
Anno
2014
Pagine
530
ISBN
9789350908457
180,00 €
I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

Dermatopathology is a subspecialty of both dermatology and pathology that studies causes and effects of skin disorders at a microscopic level.

This colour atlas is a comprehensive guide to the diagnosis and management of dermatological disorders by correlating pathological results with clinical features. Written from the perspective of both pathologists and dermatologists, the book begins with an introduction to the normal pattern of skin.

Each of the following chapters examines a different skin disorder, first providing a detailed description of the disease and its clinical features, then criteria for diagnosis, differential diagnosis and potential pitfalls.

Written by an internationally recognised author team from Utah and Pennsylvania, this invaluable guide is highly illustrated with nearly 800 clinical and histological photographs with detailed descriptions.

 

Key points

  • Comprehensive guide to diagnosis and management of skin diseases through pathology
  • Highly useful for both dermatologists and pathologists
  • Internationally recognised US author team
  • Includes nearly 800 clinical and histological photographs

Author information

Loren E Clarke MD
Vice President of Medical Affairs, Dermatology Unit Myriad Genetics, Inc/MYGN, Salt Lake City, Utah, USA

Jennie T Clarke MD
Associate Professor of Dermatology

Klaus F Helm MD
Professor of Dermatology and Pathology

Both at Milton S Hershey Medical Centre, Penn State University, Hershey, Pennsylvania, USA

 

Contents

1.

Th

e Normal Skin Pattern

1

Findings within Stratum Corneum

3

F

indings within the Dermis

8

2.

Th

e Spongiotic and Psoriasiform Patterns

19

The Spongiotic Pattern

21

S

imulators of Spongiotic Dermatitis

29

The P

soriasiform Pattern

37

3.

Th

e Interface and Perivascular/Periadnexal Patterns

45

The Vacuolar Pattern

47

I

nterface Drug Eruption

55

The L

ichenoid Pattern

58

The Pit

yriasiform Pattern

70

The I

nterface and Perivascular/Periadnexal Patterns

72

4.

Th

e Blistering and Acantholytic Patterns

81

The Intraepidermal Blistering Pattern

85

The S

ubepidermal Blistering Pattern

103

5.

F

ollicular Processes

117

Infectious Bacterial Folliculitis

119

M

ajocchi’s Granuloma

120

H

erpes Zoster

121

N

oninfectious Causes of Folliculitis

122

Alop

ecia

125

6.

Th

e Nodular and Diffuse Dermal Infiltrative Patterns

133

The Granulomatous Pattern

135

The P

alisading Granulomatous Pattern

167

The N

eutrophilic/Suppurative Dermatitis Pattern

172

The Diffus

e Histiocytic Dermatitis Pattern

182

The L

ymphoplasmacytic Dermatitis Pattern

192

D

ermal Infestations and Arthropod Bite Reactions

194

7.

Th

e Vasculopathic Pattern

199

The Occlusive Vasculopathy Pattern

201

The A

cute Vasculitis Pattern

208

The F

ibrosing Vasculitis Pattern

216

V

asculitis with Macrophages/Granulomas

219

8.

Panniculitis

223

Septal Panniculitis

225

L

obular Panniculitis Lymphocytes Predominate

227

L

obular Panniculitis—Neutrophils Predominate

229

L

obular Panniculitis—Histiocytes Predominate

230

N

oninflammatory Panniculitides

232

9.

F

ibrosing Dermatitis

235

Diseases with Decreased Number of Fibroblasts

237

Dis

eases with Increased Number of Fibroblasts

241

Contents

xii

10.

Th

e Depositional Pattern

247

Deposits of Amorphous Eosinophilic Material (“Hyaline” Deposition)

249

Am

yloidoses

249

Mucinous/Myxoid Deposits

254

L

ichen Myxedematosus

254

Pr

etibial Myxedema (Localized Myxedema)

255

Other D

eposits

256

G

out (and Pseudogout)

256

C

alcinosis Cutis (and Osteoma Cutis)

257

11.

Th

e Melanocytic Tumors

259

Cytologically Banal Melanocytes Confined to the Epidermis

262

C

ytologically Atypical Melanocytes Confined to the Epidermis

268

C

ompound or Intradermal Neoplasms That are Cytologically Banal

272

C

ompound or Intradermal Neoplasms Composed of Spindled and/or Epithelioid Melanocytes:

Spitz’s and Reed’s Nevi

290

Pr

edominantly Dermal Tumors Composed of Pigment Synthesizing Melanocytes: The “Blue Nevus” Variants

293

C

ompound or Intradermal Neoplasms Composed of Markedly Atypical Melanocytes

301

12.

E

pithelial Neoplasms

325

Non-Neoplastic Epidermal Proliferations

327

B

enign Keratinocytic Neoplasms

331

M

alignant Tumors Arising from Epidermis

340

13.

A

dnexal Neoplasms

347

Criteria for Sebaceous Differentiation

349

T

ypes of Sebaceous Neoplasms

349

F

ollicular Neoplasms

354

F

ollicular Neoplasms Differentiating towards Infundibulum and Isthmus

354

T

umor of Hair Matrix

360

T

umors of External Root Sheath

361

T

umors of Hair Germ

362

T

umors of Hair Mesenchyme

364

A

pocrine Neoplasms

366

Cr

iteria for Apocrine Differentiation

366

N

eoplasms Exhibiting Follicular-Sebaceous Apocrine Differentiation

366

T

umors Exhibiting both Eccrine and Apocrine Variants

368

P

urely Apocrine Neoplasms

371

E

ccrine Neoplasms

373

Cr

iteria for Eccrine Differentiation (Diagnosis of Exclusion)

373

E

ccrine Neoplasms

373

C

ysts

376

14.

Th

e Mesenchymal Tumors

381

Paucicellular or Patternless Tumors

383

The F

ascicular and Storiform Tumors

399

The M

yxoid Tumors

423

The E

pithelioid Tumors

434

The L

ipomatous Tumors

444

The V

ascular Tumors

451

The P

leomorphic Tumors

472

The H

istiocytoid Tumors

475

The R

ound Cell Tumors

479

15.

Th

e Cutaneous Hematolymphoid Neoplasms

481

The Epidermotropic/Adnexotropic Pattern

483

The D

ermal ± Subcutaneous Pattern

492

The S

ubcutaneous Pattern

509

Index

511

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