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Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Clinical Management of Acute Lymphoblastic Leukemia
From Bench to Bedside
Litzow, Raetz
Editore
Springer
Anno
2022
Pagine
37
ISBN
9783030851491
110,00 €
DA SCONTARE
This book provides a state-of-the-art overview of acute lymphoblastic leukemia (ALL). The first section of the book presents the translational science behind ALL, reviewing molecular pathways and targets in B- and T-cell ALL, as well as techniques and application of minimal residual disease testing. The second section spotlights ALL management strategies for patients across the spectrum, from infants to the elderly. The final section outlines current and new advances in ALL treatment, including new monoclonal antibodies and allogenic and autologous HSCT.
Written by experts in the field, Clinical Management of Acute Lymphoblastic Leukemia: From Bench to Bedside is a valuable resource that will guide patient management, stimulate investigative efforts, and increase understanding of the biologic underpinnings of the disease.
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Front Matter
Pages i-xi
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Translational Science
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Front Matter
Pages 1-1
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Molecular Pathways and Targets in B-Cell Progenitor Acute Lymphoblastic Leukemia
- Kathryn G. Roberts, Charles G. Mullighan
Pages 3-32
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Genetic Mechanisms in T-Cell Acute Lymphoblastic Leukemia
- Francesca Gianni, Adolfo Ferrando
Pages 33-46
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Minimal Residual Disease in Acute Lymphoblastic Leukemia: Techniques and Application
- Xueyan Chen, Brent L. Wood
Pages 47-72
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Therapeutics
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Front Matter
Pages 73-73
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Treatment of Pediatric B- and T-Cell Acute Lymphoblastic Leukemia
- Laura E. Hogan, Luke D. Maese, Keith J. August, Jennifer L. McNeer
Pages 75-104
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- Shimoli V. Barot, Anjali S. Advani
Pages 105-133
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- Erin H. Breese, Rishi S. Kotecha, Erin M. Guest
Pages 135-148
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Treatment of Elderly Patients with Acute Lymphoblastic Leukemia
- Marc Schwartz, Matthew Wieduwilt
Pages 149-169
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Treatment of Childhood Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
- Melissa A. Burns, Lewis B. Silverman
Pages 171-184
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Treatment of Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
- Oliver G. Ottmann
Pages 185-207
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Treatment of Ph-Like Acute Lymphoblastic Leukemia
- Thai Hoa Tran, Sarah K Tasian
Pages 209-234
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Prophylaxis and Treatment of Central Nervous System (CNS) Acute Lymphoblastic Leukemia
- Lauren D. Scherer, Eric S. Schafer
Pages 235-265
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Late Effects of Therapy of Acute Lymphoblastic Leukemia
- Liv Andrés-Jensen, Christoffer Johansen, Kjeld Schmiegelow
Pages 267-291
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New and Existing Modalities of Therapy
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Front Matter
Pages 293-293
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Monoclonal Antibody-Based Treatment and Other New Agents for B-Lineage Acute Lymphoblastic Leukemia
- John C. Molina, Nirali N. Shah
Pages 295-328
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New Agents for the Treatment of T-Cell Acute Lymphoblastic Leukemia
- Sunil S. Raikar, David T. Teachey, Nathan P. Gossai
Pages 329-351
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The Development and Management of Treatment with Chimeric Antigen Receptor T Cell (CAR T)
- Colleen Annesley, Rebecca Gardner
Pages 353-372
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Hematopoietic Stem Cell Transplantation in Adults with Acute Lymphoblastic Leukemia
- Erik L. Kimble, Ryan D. Cassaday
Pages 373-404
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New and Existing Modalities of Therapy
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Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia
- Divya Subburaj, Kirk R. Schultz
Pages 405-430
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Back Matter
Pages 431-437
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