Titolo: Chronic Myeloid Leukemia

Home

/

Specialità

/

Ematologia

/

Chronic Myeloid Leukemia

Editore

Springer

Anno

2016

Pagine

255

ISBN

9783319331973

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

Dettagli Indice Recensioni (0)

This book provides state-of-the-art reviews of key issues and recent developments relating to chronic myeloid leukemia (CML), acquainting the reader with advances in research, treatment, and promotion of public health. Among the management topics addressed are the choices, advantages, and pitfalls of first-, second-, and third-line treatments; the European LeukemiaNet recommendations; management of adverse effects of tyrosine kinase inhibitors (TKI); management of CML blast crisis; management of pregnancy in the context of CML; the role of hematopoietic cell transplantation; the current experience with TKI discontinuation; and the value of interferon α in improving the outcome of TKI treatment. Various aspects of relevance to treatment outcome are discussed, including prognostic scores, molecular monitoring (principles and interlaboratory standardization), and response-related predictors of survival. Furthermore, updates are provided on the increasing prevalence of CML and its implications and on the changing cost of care for CML, taking into account the forthcoming impact of availability of generic imatinib.

Cytogenetics of Chronic Myeloid Leukemia (CML)

Balk, Bettina (et al.)

Pages 1-16
The Biology and Pathogenesis of Chronic Myeloid Leukemia

Chereda, Bradley (et al.)

Pages 17-39
The Choice of First-Line Chronic Myelogenous Leukemia Treatment

Fava, Carmen (et al.)

Pages 41-54
A Review and an Update of European LeukemiaNet Recommendations for the Management of Chronic Myeloid Leukemia

Baccarani, Michele (et al.)

Pages 55-69
Management of Adverse Events Associated with ATP-Competitive BCR-ABL1 Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

Rea, Delphine

Pages 71-87

Standardization of Molecular Monitoring for Chronic Myeloid Leukemia

Cross, Nicholas C. P. (et al.)

Pages 89-98
Epidemiology of Chronic Myeloid Leukemia

Höglund, Martin (et al.)

Pages 99-110
Prognostic Scores for Patients with Chronic Myeloid Leukemia Under Particular Consideration of Disease-Specific Death

Pfirrmann, Markus (et al.)

Pages 111-128
Response-Related Predictors of Survival in CML

Hanfstein, Benjamin (et al.)

Pages 129-145
CML Blast Crisis: Implications and Management

Hehlmann, Rüdiger (et al.)

Pages 147-160
Managing Pregnancy in Chronic Myeloid Leukemia

Palani, Renuka (et al.)

Pages 161-175
The Role of Hematopoietic Stem Cell Transplantation in Chronic Myeloid Leukemia

Gratwohl, Alois

Pages 177-196
Discontinuation or Cessation of Tyrosine Kinase Inhibitor Treatment in Chronic Myeloid Leukemia Patients with Deep Molecular Response

Mahon, Francois-Xavier (et al.)

Pages 197-206
The Interferon Alpha Revival in CML

Talpaz, Moshe (et al.)

Pages 207-230
Changing the Cost of Care for Chronic Myeloid Leukemia: The Availability of Generic Imatinib in the USA and the EU

Conti, Rena M. (et al.)

Pages 231-255