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Since the publication of the first edition, there have been advances in both the diagnosis and the management of many of the cholestatic liver diseases. Cholestatic Liver Disease, Second Edition thoroughly updates the topics previously addressed, such as primary biliary cirrhosis, primary sclerosing cholangitis, and cholestatic variants of drug hepatotoxicity and viral disease. New treatments, such as the development of the farnesoid X receptor agonists for the treatment of PBC, are highlighted. Current guidelines and areas of uncertainty are also covered. Additionally, new chapters have been added to reflect the changing landscape of cholestatic liver disease.
Cholestatic Liver Disease, Second Edition is a concise yet comprehensive summary of the current status of the field and is of value to clinicians and researchers interested in patients with cholestatic liver disease provide that will help to guide patient management and stimulate investigative efforts.
Table of Contents
Diagnosis of Cholestasis .......................................................................... 1
Andrea A. Gossard
2 Drug-Induced Cholestasis ...................................................................... 13
Einar S. Björnsson
3 Primary Biliary Cirrhosis ...................................................................... 33
Marina G. Silveira
4 Primary Sclerosing Cholangitis ............................................................. 51
Meredith Borman and Bertus Eksteen
5 IgG4 Related Cholangitis ....................................................................... 87
Said Al Mamari, Emma L. Culver, and Roger W. Chapman
6 Rare Causes of Cholestasis ..................................................................... 111
Tamir Miloh and Ozlem Pinar Bulut
7 Cholestatic Variants of Viral Disease and Alcohol ............................... 127
Mary A. Atia and Bashar Aqel
8 Cholestasis Related to Systemic Disorders ........................................... 143
Anitha Yadav and Elizabeth J. Carey
9 Complications of Cholestasis ................................................................. 163
Abrar Ahmed and Marlyn J. Mayo
10 Cholestasis Post-Liver Transplantation ................................................ 189
Denise M. Harnois and Kymberly D. S. Watt
11 Cholestasis in the Hospitalized Patient ................................................. 201
Anne M. Larson
12 Endoscopic Management of Biliary Obstruction ................................. 229
James H. Tabibian and Todd H. Baron
Index ................................................................................................................. 253
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