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Epidemiology and Etiology of Childhood ALL
Pages 1-27
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Childhood Acute Lymphoblastic Leukemia
Vora
Editore
Springer
Anno
2017
Pagine
342
ISBN
9783319397078
90,00 €
DA SCONTARE
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy.
Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail.
This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
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Clinical Presentation and Prognostic Factors
Pages 29-48
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Diagnostic Flow Cytometry and Immunophenotypic Classification
Pages 49-59
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Cytogenetics and Molecular Genetics
Pages 61-98
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Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Antileukemic Drugs
Pages 99-138
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Minimal Residual Disease (MRD) Diagnostics: Methodology and Prognostic Significance
Pages 139-162
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First Line Treatment: Current Approach
Pages 163-181
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Targeted Therapy and Precision Medicine
Pages 183-200
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Monoclonal Antibodies in Pediatric Acute Lymphoblastic Leukemia
Pages 201-237
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Cellular Therapy
Pages 239-254
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Relapsed Acute Lymphoblastic Leukemia of Childhood
Pages 255-297
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Medical Supportive Care for Treatment-Related Toxicity in Childhood ALL
Pages 299-321
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Developing World Perspective
Pages 323-336
