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Epidemiology of Central Nervous System Metastases
Pages 3-14
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Central Nervous System Metastases
Ahluwalia, Metellus, Soffietti
Editore
Springer
Anno
2020
Pagine
421
ISBN
9783030234195
100,00 €
DA SCONTARE
This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives.
Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach.
Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.
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Pathology of Brain Metastasis
Pages 15-29
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Molecular Mechanisms in Brain Metastasis
Pages 31-41
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Genomic Characterization of Brain Metastases: Implications for Precision Medicine
Pages 43-58
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Brain Metastases Cell Partners and Tumor Microenvironment
Pages 59-71
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Liquid Biopsy Diagnosis of CNS Metastases
Pages 73-86
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Preclinical Models of Brain Metastases
Pages 87-105
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Clinical Presentation of Brain Metastases
Pages 109-115
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Epilepsy in CNS Metastases
Pages 117-125
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Safety, Tolerability, and Use of Steroids
Pages 127-137
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Anticoagulation in Patients with Brain Metastases
Pages 139-143
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Imaging of Brain Metastases: Diagnosis and Monitoring
Pages 145-158
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Metabolic Imaging of Brain Metastasis
Pages 159-171
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Clinical, Imaging, and CSF Cytological Presentation of Leptomeningeal Metastases from Solid Non-CNS Primary Tumors
Pages 173-179
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Surgery in Brain Metastasis Management: Therapeutic, Diagnostic, and Strategic Considerations
Pages 183-190
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Surgical Resection for Brain Metastases
Pages 191-198
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Stereotactic Radiosurgery for Brain Metastases
Pages 199-238
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Whole Brain Radiotherapy (WBRT) for Brain Metastases
Pages 239-245
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Combining Radiosurgery and Systemic Therapies for Treatment of Brain Metastases
Pages 247-258
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Brain Metastases from Lung Tumors
Pages 259-266
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Current Treatment Strategies in Breast Cancer Brain Metastases
Pages 267-279
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Management of Melanoma Brain Metastasis
Pages 281-287
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Miscellaneous Metastases
Pages 289-299
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Treatment of Leptomeningeal Metastases
Pages 301-311
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Neurocognitive Toxicity from Radiation Therapy for Brain Metastases
Pages 315-328
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Neurological Complications of Chemotherapy
Pages 329-340
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Neurological Complications of Targeted Therapies
Pages 341-363
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Neurological Complications of Immune-Based Therapies
Pages 365-372
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Health-Related Quality of Life Related to Toxicity Treatments in Central Nervous System Metastases
Pages 373-382
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Prognostic Indices for Patients with Brain Metastases
Pages 385-396
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Prevention Strategies for Brain Metastasis
Pages 397-406
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Clinical Trials: Endpoints and Outcome Assessment
Pages 407-421
