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Central Nervous System and Dedifferentiation
Pages 1-17
This book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications.
The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower organisms and mammalians, respectively. The final part reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases, while also outlining the prospects of and future research directions in cell dedifferentiation and regenerative medicine.
The main purpose of the book is to underline the importance of cell dedifferentiation in stem cell and regenerative medicine by providing a systematical review of dedifferentiation in all body systems, together with the latest reliable evidence.
Central Nervous System and Dedifferentiation
Pages 1-17
Peripheral Nerve Regeneration and Dedifferentiation
Pages 19-37
Dedifferentiation and the Heart
Pages 39-64
Dedifferentiation and Kidney System
Pages 65-90
Dedifferentiation and Musculoskeletal Repair and Regeneration
Pages 91-116
Dedifferentiation and Skin Regeneration
Pages 117-131
Dedifferentiation and Vision System
Pages 133-162
Blood Vessel Repair, Atherosclerosis, and Dedifferentiation
Pages 163-173
Dedifferentiation and Adipose Tissue
Pages 175-193
Dedifferentiation and Organ Regeneration
Pages 195-245
Dedifferentiation and Regenerative Medicine: The Past and the Future
Pages 247-271
Authors’ Related Publications
Pages 273-280
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