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Biology and Pathophysiology of Bone Metastasis in Prostate Cancer
Pages 1-12
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Bone Metastases from Prostate Cancer
Biology, Diagnosis and Management
Bertoldo, Boccardo, Bombardieri, Evangelista, Valdagni
Editore
Springer
Anno
2017
Pagine
293
ISBN
9783319423265
110,00 €
DA SCONTARE
This book presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response. The coverage includes discussion of all of the best available options (laboratory, radiology, and nuclear medicine) for achieving early diagnosis and both established and novel therapeutic approaches. Detailed information is provided on hormonal manipulations, bone-targeted agents, vaccines, taxanes, and other treatments that are enriching the therapeutic armamentarium. The editors can be considered leaders in the field, with great experience in diagnostic and clinical oncology and research, and the authors are experts in diverse specialties. This ensures a multidisciplinary approach, mirroring the current situation in which treatment in patients with bone metastases is undertaken by a team of specialists and health professionals in a variety of fields.
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Markers of Bone Turnover in Bone Metastasis from Prostate Cancer
Pages 13-23
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Bone Homing and Metastasis
Pages 25-32
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Markers of Prostate Cancer: The Role of Circulating Tumor Markers in the Management of Bone Metastases
Pages 33-45
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Circulating Tumor Cells (CTCs) and Metastatic Prostate Cancer (mPCa)
Pages 47-59
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Nuclear Medicine Modalities to Image Bone Metastases with Bone-Targeting Agents: Conventional Scintigraphy and Positron-Emission Tomography
Pages 61-74
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Detection of Bone Metastases and Evaluation of Therapy Response in Prostate Cancer Patients by Radiolabelled Choline PET/CT
Pages 75-85
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Imaging of Glycolysis with 18F-FDG PET
Pages 87-94
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New Radiopharmaceutical Markers for Metabolism and Receptor
Pages 95-104
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Bone Metastases from Prostate Cancer: Hormonal Therapy
Pages 105-120
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Chemotherapy
Pages 121-133
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Combinations of Hormonal Therapy and Chemotherapy
Pages 135-146
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Surgery: Treatment of Oligometastatic Disease
Pages 147-161
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Bone Metastases from Prostate Cancer: Radiotherapy
Pages 163-180
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Bone-Targeted Agents
Pages 181-192
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Bone-Seeking Radionuclide for Therapy
Pages 193-207
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New Frontiers in Treatment
Pages 209-221
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Approaches for Assessment of Response of Bone Metastases to Therapies
Pages 223-249
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Bone Metastases from Prostate Cancer: From Symptom Control to Pain Palliation
Pages 251-270
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Economic Impact of Prostate Cancer Bone Metastases
Pages 271-279
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Multidisciplinary Approach of Prostate Cancer Patients
Pages 281-293
