Biomarkers in Inflammatory Bowel Diseases

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Gastroenterologia ed Epatologia

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Biomarkers in Inflammatory Bowel Diseases

Editore

Springer

Anno

2019

Pagine

365

ISBN

9783030114459

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

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This book provides a comprehensive and complete overview of biomarkers in clinical practice for inflammatory bowel disease (IBD) bringing together the literature in a clear and concise manner. The book bridges the gap between growing knowledge at the bench and current and future applications of biomarkers in clinical practice.

The central structure of the book focuses on prognostic and predictive biomarkers in IBD with an emphasis on the fields of research and scientific techniques (genomics, proteomics and metabonomics) that have led to biomarker discovery and places these biomarkers within a clinical context to help understand their utility in clinical practice.

This book will be of use to clinicians who have an interest in using biomarkers in clinical practice as well as clinician researchers and scientists involved in the biomarker research pipeline.

The author team comprises experts from around the world in order to bring together the literature in an effort to inform clinicians and researchers about the current state-of-the art in biomarker discovery. It is intended to assist future research efforts and indicate how biomarkers might be best applied to clinical practice both at present and in the future.

Introduction

Rickard, James (et al.)

Pages 1-6
Clinical Risk Factors: Lessons from Epidemiology

Kurti, Zsuzsanna (et al.)

Pages 9-22
Disease Modification in Crohn’s Disease

Allen, Patrick B. (et al.)

Pages 23-29
Personalized Medicine - Dream or Reality?

Spencer, Elizabeth A. (et al.)

Pages 31-44
Clinical Trial Design to Facilitate Biomarker Discovery

Strik, Anne S. (et al.)

Pages 45-53

Luminal Crohn’s Disease

Lynn, Amanda M. (et al.)

Pages 57-71
Fibrosis and Stricturing Disease in Crohn’s Disease

Kurada, Satya V. (et al.)

Pages 73-87
Postoperative Crohn’s Disease

Patwala, Kurvi (et al.)

Pages 89-97
Perianal Crohn’s Disease

Mak, Wing Yan (et al.)

Pages 99-118
Biomarkers in Acute Severe Ulcerative Colitis

Choy, Matthew C., MBBS, BMedSci, FRACP (et al.)

Pages 121-130
Chronic Active Ulcerative Colitis

Vaughan, Rose (et al.)

Pages 131-140
Refractory Proctitis

Lawrance, Ian Craig

Pages 141-153
UC Surveillance

Choi, Chang-Ho Ryan (et al.)

Pages 155-167
The Role of Biomarkers in the Ileal Anal Pouch

Segal, Jonathan P. (et al.)

Pages 169-180
Extra-intestinal Manifestations in Inflammatory Bowel Disease: Diagnosis and Management

Paramsothy, Ramesh (et al.)

Pages 183-189
Primary Sclerosing Cholangitis Overlapping with IBD

Sabino, João (et al.)

Pages 191-204
Pregnancy and IBD

Flanagan, Emma (et al.)

Pages 205-215
Nutrition in IBD

Grover, Zubin (et al.)

Pages 217-231
Therapeutic Drug Monitoring in Inflammatory Bowel Disease: Optimising Therapeutic Effectiveness of Thiopurines

Srinivasan, Ashish (et al.)

Pages 233-241
Therapeutic Drug Monitoring in Inflammatory Bowel Disease: Optimising Therapeutic Effectiveness of Biologics

Srinivasan, Ashish (et al.)

Pages 243-255
Drug Toxicity: Personalising IBD Therapeutics – The Use of Genetic Biomarkers to Reduce Drug Toxicity

Walker, Gareth (et al.)

Pages 257-269
Biomarkers for Remote Monitoring

Weimers, Petra (et al.)

Pages 271-278
Exposome and Diet

Seidelin, Jakob (et al.)

Pages 281-291
The Microbiome in IBD

Peyrottes, Agathe (et al.)

Pages 293-301
Metabolic Profiling in IBD

Glymenaki, Maria (et al.)

Pages 303-312

Innate and Adaptive Immunology

Noor, Nurulamin M. (et al.)

Pages 313-321
Genetic and Genomic Markers for Prognostication

Noor, Nurulamin M. (et al.)

Pages 323-331
Risk Alleles for Drug Targets: Genomic Markers of Drug Response

Ungaro, Ryan (et al.)

Pages 333-341
Big Data Meets Real World! The Use of Clinical Informatics in Biomarker Research

Singh, Siddharth

Pages 345-352
Bringing It Altogether: A Systems Biology Approach to Biomarkers in Inflammatory Bowel Disease

Fiocchi, Claudio

Pages 353-358