Non ci sono recensioni
Enzymes and Coenzymes (A Brief, Boring but Necessary Preamble)
Pages 1-5
This book discusses and explains the importance of biochemistry knowledge in understanding what happens to patients during anesthesia and/or to those being in intensive care. It covers a wide range of topics, such as Cerebral Edema, Shock, Blood-Brain Barrier, The Pulmonary surfactant, The Acid – Base equilibrium, Local anaesthetics, Perineural adjuvants, Normobaric Oxygen Therapy, Theories of Narcosis. Hyperventilation effects and consequences are also presented. For instance, by hyperventilating a patient with a PaCO2 significantly below 25 mmHg, we risk blocking pyruvic acid carboxylation and transforming it into oxalacetic acid, which in turn knocks out the Krebs cycle, possibly leading to a complication, i.e. to metabolic acidosis and not to compensation for respiratory alkalosis. It is also worth remembering that vitamins are actually molecules of pretty considerable potency and should not be simply intended as integrators. If we inject a patient under intensive care with vitamin C, this not only plays a capillary-protective role but facilitates the conversion of dopamine to noradrenaline. As far as vitamin B6 goes, not only is it the most natural of antiemetics but the coenzyme responsible for transforming glutamate as one of the most powerful excitatory mediators into GABA, one of the fiercest inhibitors. Anesthesiological and intensive care practice require a detailed biochemistry knowledge to avoid onset of complications and/or to deal with unexpected events promptly and appropriately.
The book is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees and residents.
Enzymes and Coenzymes (A Brief, Boring but Necessary Preamble)
Pages 1-5
Anaerobic Glycolysis or Embden–Meyerhof Pathway
Pages 7-14
Tricarboxylic Acids Cycle or Krebs Cycle
Pages 15-21
Glutamate – GABA Collateral Cycle
Pages 23-34
Hexose-Monophosphate Shunt or Horecker Cycle (The Sleep Pathway)
Pages 35-47
Neurotransmitters
Pages 49-70
Blood–Brain Barrier
Pages 71-74
Shock
Pages 75-95
Cerebral Oedema
Pages 97-117
Pulmonary Surfactant
Pages 119-121
When the Mind Does Not Work as It Should
Pages 123-138
Thiamine (Vitamin B1)
Pages 139-159
Normobaric Oxygen Therapy(a little used therapeutic system)
Pages 161-166
Acid–Base Equilibrium(cliche paper yellow)
Pages 167-188
Theories of Narcosis
Pages 189-205
Local Anaesthetics
Pages 207-223
Perineural Adjuvants
Pages 225-237
The Grand Design
Pages 239-247
Epilogue and Farewell
Pages 249-250
Sei sicuro di voler eseguire questa azione?