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Basic Radiation Physics
Pages 3-35
This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and
its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Basic Radiation Physics
Pages 3-35
Radiation Safety and CT Dosimetry in PET/CT Imaging
Pages 37-64
Radiation Dosimetry of PET Imaging
Pages 65-76
Chemistry of PET Radiopharmaceuticals: Labelling Strategies
Pages 79-103
Quality Control of PET Radiopharmaceuticals
Pages 105-126
Regulation of PET Radiopharmaceuticals Production in Europe
Pages 127-143
Regulatory Aspects of PET Radiopharmaceutical Production in the United States
Pages 145-170
PET Physics and Instrumentation
Pages 173-197
PET/MR: Basics and New Developments
Pages 199-228
PET Calibration, Acceptance Testing, and Quality Control
Pages 229-255
PET Image Reconstruction: Methodology and Quantitative Accuracy
Pages 259-284
Image Processing and Analysis of PET and Hybrid PET Imaging
Pages 285-301
Basics and Advances of Quantitative PET Imaging
Pages 303-322
Compartmental Modeling in PET Kinetics
Pages 323-352
Partial Volume Correction in PET Imaging
Pages 355-378
Motion Artifacts and Correction Techniques in PET/CT
Pages 379-396
Physiologic and Molecular Basis of PET in Cancer Imaging
Pages 399-427
Clinical Applications of PET/CT in Oncology
Pages 429-450
Cardiac PET Imaging: Principles and New Developments
Pages 451-483
PET in Neurological and Psychiatric Disorders: Technologic Advances and Clinical Applications
Pages 485-535
Role of PET/CT in Pediatric Malignancy
Pages 537-575
Role of PET/CT in Radiotherapy Treatment Planning
Pages 577-608
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