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This book provides a wealth of images and extensive information on circulating tumor cells (CTCs) and other cells usually observed in blood from patients with cancer, such as giant macrophages, and circulating tumor microemboli (CTM).
The field of “liquid biopsy” began with the analysis of CTCs in the early 2000s. In the beginning, molecular techniques were developed to detect these cells in the blood. However, it has since become clear that CTCs initially require a cytopathological analysis to be detected without false positive and negative results. After detection, molecular analysis can be subsequently performed.
Cancer is an important cause of mortality, especially when detected in late stages. Even with all the advances that have been made in its treatment, cancer is still challenging, as many patients do not respond to any therapy. Many health agencies have considered early diagnosis as a feasible tool. In this context, it is of the utmost importance to know the morphology and characteristics of CTCs to determine a correct diagnosis. Currently much of the scientific community is committed to expanding our knowledge of CTCs, and this work makes a valuable contribution, presenting hundreds of cell images from patients with various types of cancer, in many different stages of disease, and after receiving various treatments.
The Atlas of Liquid Biopsy: Circulating Tumor Cells and Other Rare Cells in Cancer Patients’ Blood is an essential reference guide for all physicians, biologists, biomedics, and professionals working at clinical and research laboratories, hospitals and research centers.
Circulating Tumor Cells: Brief Overview of Methods for Detection
Pages 1-8
Chinen, Ludmilla Thomé Domingos
CTCs in Solid Tumors. Clinical Applications of Circulating Tumor Cells in Breast Cancer
Pages 9-25
Castro, Douglas Guedes (et al.)
Circulating Tumor Cells in Head and Neck Cancer
Pages 27-45
Oliveira, Thiago Bueno
Circulating Tumor Cells in Colorectal Cancer
Pages 47-63
Souza e Silva, Virgilio (et al.)
Circulating Tumor Cells in the context Non-small Cell Lung Cancer
Pages 65-92
Torres, Jacqueline Aparecida
Circulating Tumor Cells in Prostate Cancer
Pages 93-102
Tariki, Milena Shizue
Circulating Tumor Cells in Gastric Cancer
Pages 103-126
Torres, Jacqueline Aparecida (et al.)
Circulating Tumor Cells in Mesenchymal Tumors
Pages 127-147
Braun, Alexcia Camila (et al.)
Circulating Tumor Microemboli: Characteristics and Clinical Relevance
Pages 149-161
Abdallah, Emne Ali
Circulating Endothelial Cells: Characteristics and Clinical Relevance
Pages 163-168
Tarazona, José Gabriel Rodríguez (et al.)
Giant Macrophages: Characteristics and Clinical Relevance
Pages 169-184
Earl, Julie (et al.)
In Vitro and In Vivo Models of Circulating Tumor Cells
Pages 185-195
Ruano, Anna Paula Carreta (et al.)
Brief Summary and Perspectives for CTCs
Pages 197-201
Tarazona, José Gabriel Rodríguez (et al.)
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