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Atlas of Hematopathology with 100 Case Studies is a practical guide useful for pathologists and hematologists, residents and fellows, laboratory directors, researchers, and students in the field of hematology, cytogenetic, and molecular pathology. The book offers important information to practicing physicians and those in pathology and hematology training to improve their diagnostic skills. It covers the most important aspects of hematopathology, including classifications, clinical symptoms, hematopathologic features, diagnostic criteria, differential diagnosis, and the use and importance of ancillary testing, such as immunohistochemistry, flow cytometry, and cytogenetics. |
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1. Bone marrow evaluation.
2. White blood cells.
3. Red blood cells.
4. Dendritic cell and histiocytic disorders.
5. Myelodysplastic and related neoplasms.
6. Myeloproliferative Neoplasms and related disorders.
7. Acute Myeloid Leukemias (AML) and related disorders.
Definition and morphologic features of immature cells
AML with recurrent genetic abnormalities
AML with myelodysplasia-related changes
Therapy-related AML
AML not otherwise specified
AML minimally differentiated
AML without maturation
AML with maturation
Acute myelomonocytic leukemia
Acute monoblastic and monocytic leukemia
Acute erythroid leukemia
Acute megakaryoblastic leukemia
Acute basophilic leukemia
Acute panmyelosis with myelofibrosis
Myeloid sarcoma
Myeloid proliferations related to Down syndrome
8. B-Lymphoblastic Leukemia/Lymphoma (B-ALL).
Definition and classification
A. lymphoblastic leukemia/lymphoma with recurrent genetic abnormalities
B-LBLL with t(9;22)(q34.1;q11.2);BCR-ABL1
B-LBLL with t(4;11)(q21;q23) (AFF1- KMT2A) and variants
B-LBLL with t(12;21)(p13.2;q22.1); ETV6-RUNX
B-LBLL with t(1;19)(q23;p13.3);TCF3-PBX1
B-LBLL with t(5;14)(q31.1;q32.3) IL3-IGH
B-LBLL with hyperdiploidy
B-LBLL with hypodiploidy
B-LBLL, BCR-ABL1-like
B-LBLL with iAMP21=
B. lymphoblastic leukemia/lymphoma, not otherwise specified (NOS)
9. Mature B-Cell Neoplasms.
Definition and classification
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)
Prolymphocytic leukemia
Hairy cell leukemia
Lymphoplasmacytic lymphoma
Splenic marginal zone B-cell lymphoma
Nodal marginal zone B-cell lymphoma
Mucosa-associated lymphoid tissue (MALT) lymphoma
Mantle cell lymphoma
Follicular lymphoma
Large B-cell lymphoma subtypes
Plasmablastic lymphoma
Burkitt lymphoma
10. T-Lymphoblastic Leukemia/Lymphoma (T-ALL)
Definition and classification
Early T-cell precursor ALL
Early cortical T-ALL
Late cortical T-ALL
Medullary T-ALL
Cytogenetic and molecular studies
11. T and NK Cell Neoplasms.
Definition and classification
Large granular lymphocytic leukemia
Extranodal NK/T-cell lymphoma, nasal type
T-cell prolymphocytic leukemia
Adult T-cell leukemia/lymphoma
Hepatosplenic T-cell lymphoma
Mycosis Fungoides and Sézary Syndrome
Angioimmunoblastic T-cell lymphoma
Anaplastic large cell lymphomas
Peripheral T-cell lymphoma, not otherwise specified
12. Hodgkin Lymphoma
Definition and classification
A. Nodular lymphocyte predominant Hodgkin lymphoma
B. Classical Hodgkin Lymphoma
Nodular sclerosis classical Hodgkin lymphoma (NSHL)
Mixed cellularity classical Hodgkin lymphoma (MCHL)
Lymphocyte-rich classical Hodgkin lymphoma (LRHL)
Lymphocyte-depleted classical Hodgkin lymphoma (LDHL).
13. Plasma Cell Neoplasms
Definition and classification
Monoclonal gammopathy of undetermined significance (MGUS)
Plasma cell myeloma
Plasma cell leukemia
Osteosclerotic myeloma (POEMS syndrome)
Plasmacytoma
Immunoglobulin light and heavy chain disease
14. Reactive Lymphadenopathies
Definition and classification
Follicular Hyperplasia
Castleman disease
Sinus histiocytosis with massive lymphadenopathy
Lymphohistiocytic hemophagocytosis
Sarcoidosis
Toxoplasmosis
Cat-scratch disease
Cytomegalovirus
Infectious mononucleosis
Kikuchi disease
Kimura disease
Dermatopathic lymphadenitis
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