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* 2011 BMA Book Awards - Highly Commended in Neurology * Atlas of Clinical Neurology, by David Perkin, Douglas C. Miller, Russell Lane, Maneesh C. Patel, and Fred H. Hochberg, delivers the most powerful, clinically oriented image collection of any reference in your specialty - to help you accurately diagnose any condition you see in practice! Approximately 2,000 large, high-quality images - 1,000 in full color - capture the characteristic physical examination and imaging findings of every type of neurological disorder. All of the diagnostic imaging studies have been updated to reflect the dramatic advances in neuroimaging. Updates throughout include a brand-new chapter on myopathies and myasthenia, expanded coverage of epilepsy, and an entire chapter devoted to extrapyramidal disorders. Online access at www.expertconsult.com enables you to reference this masterwork from any computer and download all of the images. The result is the ultimate diagnostic resource in neurology! |
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Table of Contents:
1 Neurologic 1Investigation
The Cerebrospinal Fluid, 1
Plain Radiography, 1
Ultrasound: Noninvasive Scanning, 2
Computed Tomographic Scanning, 2
Magnetic Resonance Imaging, 2
Digital Subtraction Angiography, 13
Interventional Techniques, 13
Radioisotope Imaging, 15
Electrophysiology, 16
Electromyography, 20
Biopsy, 22
2 Motor Neuron 28and Peripheral Nerve Diseases
Pathogenesis of Motor Neuron Disease, 28
Clinical Variants of Classic Motor Neuron Disease, 28
Atypical Amyotrophic Lateral Sclerosis, 30
Monomelic Amyotrophy, 31
Acquired Sporadic Motor Neuron Diseases, 31
Genetic Motor Neuron Diseases, 31
Spinal Muscular Atrophies, 31
Other Forms of Spinal Muscular Atrophy, 33
Bulbar Syndromes, 33
Familial Motor Neuron Disease, 33
Peripheral Nerve Diseases, 33
Peripheral Neuropathy, 33
Genetically Determined Neuropathies, 34
Charcot-Marie-Tooth Disease, 34
Hereditary Neuropathy with Liability to Pressure Palsies, 36
Hereditary Sensory and Autonomic Neuropathy, 36
Hereditary Neuralgic Amyotrophy, 36
Neuropathies as Part of Genetic Systemic Neurologic Diseases, 37
Porphyria, 37
Disorders of Lipid Metabolism, 38
Familial Amyloid Polyneuropathies, 38
Metachromatic Leukodystrophy, 38
Polyneuropathies in Acquired Systemic Diseases, 39
Diabetic Neuropathy, 39
Nutritional and Deficiency Disorders, 41
Paraproteinemic Neuropathies, 41
Infectious and Postinfectious Causes, 42
Chronic Inflammatory Demyelinating Polyradiculoneuropathy, 43
Connective Tissue Disorders, 44
Toxic Neuropathies, 44
Paraneoplastic Neuropathies, 44
Neuropathy of Unknown Cause, 45
The Mononeuropathies, 45
3 Myopathies 57and Myasthenia
Genetic Myopathies, 57
Muscular Dystrophies and Related Disorders, 57
Myotonic Dystrophies and Non-dystrophic Myotonias, 65
Congenital Myopathies, 69
Mitochondrial Myopathies, 70
Metabolic Myopathies, 72
Acquired Myopathies, 74
Inflammatory Immune-Mediated Myopathies, 74
Myopathies in Systemic Diseases, 77
Toxin- and Drug-Induced Myopathies, 79
Myasthenia Gravis and Other Neuromuscular Transmission Disorders, 81
4 Cerebrovascular 99Disease: Cerebral Infarction
Anatomy, 99
Classification, 99
Cerebral Infarction, 99
Pathologic and Physiologic Consequences of Cerebral Infarction, 102
Investigation, 103
Clinical Syndromes, 109
Other Causes of Cerebral Infarction, 116
Hypertensive Encephalopathy, 121
Clinical Examination, 121
5 Cerebral Hemorrhage 143and Other Cerebrovascular Disorders
Cerebral Hemorrhage, 143
Clinical Features, 143
Investigation of Suspected Hematoma, 146
Nonhypertensive Intracerebral Hemorrhages, 147
Vascular Malformations, 147
Cerebral Amyloid Angiopathy, 153
Coagulation Disorders, 153
Aneurysms, 154
Cerebral Venous Thrombosis, 158
6 Dementia Syndromes 169
Alzheimer’s Disease, 169
Macroscopic Appearance, 169
Microscopic Appearance, 169
Clinical Features, 169
Investigation, 170
Treatment, 170
Dementia and Lewy Bodies, 170
Frontotemporal Dementia and Lobar Atrophies, 170
Frontotemporal Lobar Degeneration with Tau Pathology, 172
Pick’s Disease, 172
Familial Taupathies, 174
Frontotemporal Lobar Degeneration with Ubiquitin-Only Immunoreactive Changes, 174
Arteriosclerotic Dementia, 174
Imaging, 174
7 Extrapyramidal 176Disorders
Parkinson’s Disease, 176
Clinical Features, 176
Investigation, 176
Treatment, 176
Postencephalitic Parkinsonism, 180
Atypical Parkinsonian Disorders, 182
Progressive Supranuclear Palsy, 182
Frontotemporal Dementia and Parkinsonism, 183
Corticobasal Degeneration, 184
Multisystem Atrophy, 185
Other Parkinsonian Syndromes, 186
Arteriosclerotic Parkinsonism, 186
Dystonia, 186
Primary Dystonia, 186
Secondary Dystonias, 189
Choreiform and Ballistic Movements, 191
Other Choreiform Disorders, 193
8 Intracranial Tumors: 201Paraneoplastic (Nonmetastatic) Neurologic Syndromes
Clinical Features of Intracranial Tumors, 201
The Investigation of Intracranial Tumors, 202
Treatment of Brain Tumors: General Considerations, 206
Specific Tumors, 207
Metastases, 207
Primary Intraaxial Brain Tumors, 207
Tumors in or Adjacent to the Ventricular System, 214
Embryonal CNS Tumors, 216
Nonneuroepithelial Intraaxial CNS Tumors, 217
Primary Extraaxial Brain Tumors, 219
The Nonmetastatic (Paraneoplastic) Cerebral and Cerebellar Syndromes, 224
9 Spinal Tumors 249and Paraneoplastic Disorders
Clinical Features of Spinal Tumors, 249
Investigation of Spinal Tumors, 249
Specific Tumors, 253
Intramedullary Tumors, 253
Tumors of the Spinal Meninges, 255
Tumors of the Epidural Space and Spine, 256
10 Developmental 266and Familial Disorders
Neural Tube Defects, 266
Spina Bifida Occulta, 266
Spina Bifida Cystica, 266
Chiari Malformations, 267
Dandy-Walker Syndrome, 268
Lhermitte-Duclos Syndrome, 268
Agenesis of the Corpus Callosum, 269
Anomalies of the Septum Pellucidum, 269
Neuronal Migration Defects, 270
Disorders of Diverticulation, 271
Neuronal Heterotopias in Cerebral White Matter, 272
Arachnoid Cysts, 272
Porencephaly, 272
Hydrocephalus, 273
Normal Pressure Hydrocephalus, 274
Tuberous Sclerosis (Bourneville’s Disease), 275
Neurofibromatosis (Von Recklinghausen’s Disease), 276
Familial Disorders Affecting the Cerebellum, 278
11 Pain Syndromes 289and Trauma
Headache, 289
Primary Headaches, 289
Secondary Headaches, 295
Neuralgias, 298
Cranial Neuralgias, 298
Postherpetic Neuralgia, 300
Causalgia and Reflex Sympathetic Dystrophy, 300
Head Injury, 300
Severity of Head Injury, 300
Mechanisms of Brain Injury, 301
Chronic Complications of Head Injury, 304
Spinal Injury, 305
Injury to Both Bony and Neurologic Structures, 305
Spinal Cord Syndromes, 310
12 Infections 312
The Meningitides, 312
Viral Meningitis, 312
Bacterial Meningitis, 312
Tuberculous Meningitis, 313
Cryptococcal Meningitis, 314
Parenchymal Infections: Cerebritis, Encephalitis, Abscess, Subdural Empyema, 314
Fungal Encephalitis, 314
Parasitic Infection, 316
Spinal Cord Infarction, 376
Spinal Extradural Hematoma, 377
Amyloidosis, 378
Anterior Herniation of the Cord, 378
15 Cranial Neuropathies 386
The First Cranial Nerve (Olfactory), 386
The Second Cranial Nerve (Optic), 386
Orbital Tumors, 386
Pupillary Syndromes, 387
The Third Cranial Nerve (Oculomotor), 389
The Fourth Cranial Nerve (Trochlear), 391
The Sixth Cranial Nerve (Abducens), 391
Orbital Lesions, 391
Brainstem Oculomotor Syndromes, 396
Other Horizontal Gaze Disorders, 401
The Fifth Cranial Nerve (Trigeminal), 401
The Seventh Cranial Nerve (Facial), 402
The Eighth Cranial Nerve (Acoustic), 405
The Ninth, Tenth, Eleventh, and Twelfth Cranial Nerves, 408
Combined Cranial Nerve Palsies, 408
16 Neurologic Aspects 413Of Systemic Disease
Radiation Damage, 413
Radiation Damage to Extracranial Vessels, 413
Alcohol and the Nervous System, 413
Central Pontine Myelinolysis, 417
Marchiafava-Bignami Disease, 418
The Neurology of Endocrine Disease, 418
Pituitary Disorders, 418
Adrenal Disorders, 418
Thyroid Disorders, 418
Parathyroid Disorders and Abnormalities of Calcium Metabolism, 418
Paget’s Disease, 418
Pancreatic Disease, 418
Neurologic Features of Vasculitis, 420
Systemic Necrotizing Vasculitis, 420
Hypersensitivity Vasculitides, 421
Systemic Granulomatous Vasculitides, 421
Connective Tissue Disorders, 422
Systemic Lupus Erythematosus, 422
Scleroderma, 422
Sjögren’s Syndrome, 423
Behçet’s Disease, 423
Vasculitis Associated with Infection, 423
Sarcoidosis, 423
Conversion Syndromes, 424
17 Epilepsy 434
Partial Seizures, 434
Generalized Seizures, 434
Causes of Epilepsy, 434
Investigation, 435
Magnetic Resonance Imaging, 436
Single-Photon Emission Computed Tomography, 439
Positron Emission Tomography, 439
Therapy, 440
Adverse Drug Effects, 441
Index, 449
Bacterial Cerebritis, 318
Cerebral Bacterial Abscess, 319
Subdural Empyema, 321
Encephalitis, 322
Viral Encephalitis, 322
Acquired Immune Deficiency Syndrome, 328
Peripheral Nerve Complications, 329
Opportunistic Viral Encephalitides in AIDS, 329
Nonviral Opportunistic Infections in AIDS, 330
Cerebral Lymphoma in AIDS, 332
CNS Diseases Caused by Spirochetes, 332
Syphilis, 332
Lyme Disease, 334
Leptospirosis, 334
Prion Disease, 335
Creutzfeldt-Jakob Disease, 335
Variant Creutzfeldt-Jakob Disease, 336
13 Multiple Sclerosis 343and Other Demyelinating Disorders
Multiple Sclerosis, 343
Pathology, 343
Pathophysiology, 345
Clinical Features, 346
Investigation, 347
Devic’s Disease (Neuromyelitis Optica), 349
Baló’s Disease, 349
Schilder’s Disease, 349
Acute Disseminated Encephalomyelitis, 350
The Leukodystrophies, 350
Lysosomal Disorders, 350
Peroxisomal Disorders, 352
Other White Matter Disorders, 352
14 Spinal Disorders 360
Degenerative Disease of the Spine, 360
Cervical Disc Disease, 360
Investigation, 360
Management, 362
Thoracic Disc Disease, 362
Lumbosacral Disc Disease, 362
Investigation of Lumbosacral Disc Disease, 363
Spinal Stenosis, 364
Paget’s Disease of the Spine, 364
Rheumatoid Arthritis and the Spine, 365
Infection, 366
Spinal Epidural Abscess, 366
Tuberculous Disease of the Spine, 367
Brucellosis, 368
Schistosomiasis, 368
HTLV-1-Associated Myelopathy, 369
Arachnoid Cysts, 369
Arachnoiditis, 369
Vascular Abnormalities of the Spine and Cord, 370
Spinal (Pial) Arteriovenous Malformations, 370
Spinal Dural Arteriovenous Fistulas, 373
Cavernous Hemangioma (Cavernoma), 373
Vertebral Body Hemangiomas, 373
Subacute Combined Degeneration of the Spinal Cord, 374
Radiation Myelopathy, 375
Syringomyelia, 375
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