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Antiphospholipid Syndrome
Current Research Highlights and Clinical Insights
Erkan, Lockshin
Editore
Springer
Anno
2017
Pagine
372
ISBN
9783319554402
130,00 €

DA SCONTARE

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.
  • A comprehensive and thorough collection of essays on all aspects of APS by internationally recognized authorities in the field
  • Presents the latest state-of-the-art information about evidence-based practice
  • Describes new treatments and diagnostic tools and the significant developments in pathophysiology of APS 
  • Of interest to all clinicians involved in the treatment and management of APS patients

This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated with low platelet or blood elements that prevent bleeding. Recently, however, even more disease states have been linked with APS, including premature heart attack, various cardiac valvular abnormalities, skin lesions, kidney disease, abnormal involuntary movement/chorea, diseases that mimic multiple sclerosis, and vascular diseases of the eye that can lead to visual loss and blindness. The International Congress on Antiphospholipid Antibodies, held every 3 years, is the venue where representatives from different disciplines gather to discuss the recent advances in APS. The conference intends to cover basic aspects of APS, such as pathogenesis, origins, genetics, intracellular and molecular events, the role of infections, as well as traditional and non-traditional clinical manifestations associated with antiphospholipid antibodies. The 15th Congress took place in September 2016. A novel aspect of the Congress was that multiple teams, chaired by Scientific Planning Committee members, used evidence-based literature reviews and expert discussions to answer specific pre-defined APS-related questions. These teams included points of view from experts in rheumatology, hematology, cardiovascular medicine, obstetrics, neurology, and immunology. The Scientific Planning Committee members also chaired the congress sessions and supervised completion of the reports that are the bases of the chapters of this book. In addition, there are two chapters included specifically written for APS patients. Much like the previous volume, dedicated to the 13th International Congress on Antiphospholipid Antibodies (April 2010), this up-to-date and comprehensive work gathers invaluable insights from a multidisciplinary team of world-renowned experts and represents the authoritative resource on causes, symptoms, diagnosis, and treatment of APS.​​

Table of contents (20 chapters)

 
  • History of Antiphospholipid Antibody

    Lockshin, Michael D. (et al.)

    Pages 3-11

  • Natural Proteins Involved in Antiphospholipid Syndrome

    Groot, Philip G. (et al.)

    Pages 15-27

  • Origin of Antiphospholipid Antibodies

    Rauch, Joyce (et al.)

    Pages 29-52

  • Recent Advances in Understanding of the Genetics of Antiphospholipid Syndrome

    Goel, Niti (et al.)

    Pages 53-75

  • Mechanisms of Antiphospholipid Antibody-Mediated Thrombosis

    Willis, Rohan (et al.)

    Pages 77-116

  • Mechanisms of Antiphospholipid Antibody-Mediated Pregnancy Morbidity

    Salmon, Jane E. (et al.)

    Pages 117-143

  • Definition and Epidemiology of Antiphospholipid Syndrome

    Unlu, Ozan (et al.)

    Pages 147-169

  • Clinical and Prognostic Significance of Non-criteria Antiphospholipid Antibody Tests

    Bertolaccini, Maria Laura (et al.)

    Pages 171-187

  • Disease and Risk Measurement Criteria in Antiphospholipid Syndrome

    Amigo, Mary-Carmen (et al.)

    Pages 189-199

  • Neuropsychiatric Manifestations of Antiphospholipid Syndrome

    Yelnik, Cécile M. (et al.)

    Pages 201-219

  • Prevention and Treatment of Thrombotic Antiphospholipid Syndrome

    Crowther, Mark (et al.)

    Pages 223-233

  • Prevention and Treatment of Obstetric Antiphospholipid Syndrome

    Jesús, Guilherme Ramires (et al.)

    Pages 235-246

  • Treatment of Non-criteria Manifestations in Antiphospholipid Syndrome

    Ugolini-Lopes, Michelle Remião (et al.)

    Pages 247-266

  • Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION)

    Barbhaiya, Medha (et al.)

    Pages 267-276

  • 15th International Congress on Antiphospholipid Antibodies Task Force on Antiphospholipid Syndrome Classification Report

    Zuily, Stéphane (et al.)

    Pages 279-290

  • 15th International Congress on Antiphospholipid Antibodies Task Force on Pediatric Antiphospholipid Syndrome Report

    Soybilgic, Arzu (et al.)

    Pages 291-306

  • 15th International Congress on Antiphospholipid Antibodies Task Force on Catastrophic Antiphospholipid Syndrome Report

    Cervera, Ricard (et al.)

    Pages 307-316

  • 15th International Congress on Antiphospholipid Antibodies Task Force on Antiphospholipid Syndrome Treatment Trends Report

    Andrade, Danieli (et al.)

    Pages 317-338

  • Antiphospholipid Syndrome: What Should Patients Know?

    Erkan, Doruk (et al.)

    Pages 341-357

  • Obstetric Antiphospholipid Syndrome: What Should Patients Know?

    Sammaritano, Lisa R. (et al.)

    Pages 359-367

 

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