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Introduction
Pages 1-6
This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.
Introduction
Pages 1-6
Warfarin
Pages 9-30
Unfractionated Heparin and Low-Molecular-Weight Heparin
Pages 31-57
Parenteral Anticoagulants: Direct Thrombin Inhibitors and Pentasaccharides
Pages 59-85
Direct Oral Anticoagulants
Pages 87-103
Anticoagulation Reversal
Pages 105-131
Transitioning Between Anticoagulants
Pages 133-150
The Anticoagulation Clinic
Pages 153-173
Perioperative Management of Anticoagulants
Pages 175-195
Acute Coronary Syndromes
Pages 197-216
Antithrombotic Therapy for Patients with Atrial Fibrillation
Pages 217-238
Anticoagulant Strategies for Electrophysiology Procedures
Pages 239-251
Anticoagulation for Cardiac Prosthetic Devices: Prosthetic Heart Valves, Left Ventricular Assist Devices, and Septal Closure Devices
Pages 253-295
Anticoagulation in Venous Thromboembolism
Pages 297-323
Thrombophilic States
Pages 325-343
Thrombophilia Testing
Pages 345-357
Heparin-Induced Thrombocytopenia
Pages 359-390
Anticoagulation Therapy in Pregnant Patients
Pages 391-408
Anticoagulation in the Elderly
Pages 409-424
Anticoagulation in the Patient with Cancer
Pages 425-440
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