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Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Antibiotic Policies
Gould, van der Meer
Editore
Springer
Anno
2011
Pagine
209
ISBN
9781441917348
140,00 €
- Explores the hypothesis that the increased use of antibiotics led subconsciously to a loss of emphasis on the importance of hygiene in the control of Hospital Acquired Infection
- Contains chapters by acclaimed authors on all the major causes of Hospital Acquired Infection, including MRSA, VRE, Clostridium difficile and multi resistant gram negative infections which are increasingly pan-resistant and untreatable
- Is an excellent source of information for students, researchers and practitioners in infection control, hospital epidemiology, antimicrobial prescribing and microbiology
Hospitals worldwide are currently suffering an epidemic of infections, generated in and spreading in those instituitions whose very “raison d’etre” is to protect and improve the health of their patients. This paradox comes at a time of possibly unprecedented investment in preventative measures (infection control). To better control these infections, however, we need to understand their causes, many of which are related, paradoxically, to the success of antibiotic therapy. It is possible that the golden era of antibiotics led subconsciously to a loss of emphasis on the importance of hygiene in the control of HAI. Moreover, the majority of HAIs are due to multiply antibiotic resistant bacteria whose emergence has been hastened by over-enthusiastic antibiotic prescribing. Accumulating evidence also suggests that antibiotics not only select for resistance but can actually increase the numbers of HAIs and even their virulence.
This comprehensive compilation, written by eminent international researchers, explores these hypothesis in the context of recent epidemiology and evidence for the success of various antibiotic stewardship measures in controlling and even reversing resistance. It contains chapters by acclaimed authors on all the major causes of HAI, including MRSA, VRE, Clostridium difficile and multi resistant gram negative infections which are increasingly pan-resistant and untreatable; the nearest thing we have yet experienced to a “Doomsday bug”.
This book is an excellent source of information for students, researchers and practitioners in infection control, hospital epidemiology, antimicrobial prescribing and microbiology.
vii
Contents
Healthcare Associated Infections—The Size of the Problem ���������������������� 1
Eimear Brannigan and Alison Holmes
The Antibiotic Paradox ���������������������������������������������������������������������������������� 15
Ian M. Gould
The Epidemiology of Pan/Extreme Drug Resistance ����������������������������������� 27
Yoshiro Hayashi and David L. Paterson
Hospital Antibiotic Stewardship to Control Resistance—How
Should It be Done? ������������������������������������������������������������������������������������������ 39
Ian M. Gould
Controlling Clostridium difficile Infection and the Role
of Antibiotic Stewardship ������������������������������������������������������������������������������� 53
Ed J. Kuijper, S. Johnson, A. Goorhuis and M. H. Wilcox
The Control of MRSA ������������������������������������������������������������������������������������ 63
Evelina Tacconelli and G. De Angelis
The Role of Antibiotic Policies in Controlling VRE ������������������������������������� 81
Abhijit M. Bal
The Control of ESBL-Producing Bacteria ���������������������������������������������������� 91
Peter M. Hawkey
Controlling Hospital-Acquired Infection due to Carbapenem-
Resistant Enterobacteriaceae (CRE) ������������������������������������������������������������� 105
Mitchell J. Schwaber, Yehuda Carmeli and Stephan Harbarth
Control of Multi-Drug Resistant Acinetobacter Infections �������������������������� 117
Paschalis Vergidis and Matthew E. Falagas
viii
The Control of Multidrug-Resistant Pseudomonas: Insights into
Epidemiology and Management �������������������������������������������������������������������� 127
Evangelos J. Giamarellos-Bourboulis
Multidrug-Resistant Infections in Low-Resource Health Care Settings ��� 141
Cara Winters and Hellen Gelband
Germ Shed Management in the United States ��������������������������������������������� 163
Kevin Outterson and Olga Yevtukhova
Required Actions to Control Antimicrobial Resistant
Healthcare-Associated Infections ������������������������������������������������������������������ 183
Inge C. Gyssens and Jos W. M. van der Meer
Index ����������������������������������������������������������������������������������������������������������������� 203
Contents
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