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- Aspects of the History and Nomenclature of Amyloid and Amyloidosis
Pages 3-8
The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue, skin, lymph node/spleen and bone marrow pathology is also covered.
Amyloid and Related Disorders, Second Edition will be invaluable to specialized and general pathologists as well as cytopathologists. Other medical professionals may also benefit from this concise update on the systemic amyloidoses.
Pages 3-8
Amyloid Diseases at the Molecular Level: General Overview and Focus on AL Amyloidosis
Pages 9-29
AA Amyloidosis
Pages 31-53
Leukocyte Cell-Derived Chemotaxin 2 Amyloidosis (ALECT2)
Pages 55-63
The Hereditary Amyloidoses
Pages 65-80
Dialysis-Associated Amyloidosis
Pages 81-94
Localized Amyloidoses and Amyloidoses Associated with Aging Outside the Central Nervous System
Pages 95-120
Amyloid Deposition in the Central Nervous System
Pages 121-131
Differential Diagnosis of Amyloid in Surgical Pathology: Organized Deposits and Other Materials in the Differential Diagnosis of Amyloidosis
Pages 135-152
Light/Heavy Chain Deposition Disease as a Systemic Disorder
Pages 153-166
Non-Randall Glomerulonephritis with Non-Organized Monoclonal Ig Deposits
Pages 167-178
Pathologies of Renal and Systemic Intracellular Paraprotein Storage: Crystalopathies and Beyond
Pages 179-194
Diagnosis of Amyloid Using Congo Red
Pages 197-211
Diagnosis of Minimal Amyloid Deposits by Congo Red Fluorescence and Amyloid Type-Specific Immunohistochemistry: A Review
Pages 213-224
Thioflavin T Stain: An Easier and More Sensitive Method for Amyloid Detection
Pages 225-227
Fat Tissue Analysis in the Management of Patients with Systemic Amyloidosis
Pages 229-248
Generic Diagnosis of Amyloid: A Summary of Current Recommendations and the Editor’s Comments on Chapters 13–16
Pages 249-259
Typing of Amyloid for Routine Use on Formalin-Fixed Paraffin Sections of 626 Patients by Applying Amyloid type-Specific Immunohistochemistry: A Review
Pages 261-272
Amyloid Typing: Experience from a Large Referral Centre
Pages 273-282
Options for Amyloid Typing in Renal Pathology: The Advantages of Frozen Section Immunofluorescence and a Summary of General Recommendations Regarding Immunohistochemistry Methods
Pages 283-293
Amyloid Typing in Plastic-Embedded Tissue by Immune-Gold-Silver Method
Pages 295-298
The Role of Immuno-Electron Microscopy in Amyloid Typing: The Experience of the Pavia Referral Center
Pages 299-310
Classification of Amyloidosis by Mass Spectrometry-Based Proteomics
Pages 311-322
The Role of Differential Proteomics in Amyloid Typing: The Experience of the Pavia Referral Center
Pages 323-330
Laboratory Support for Diagnosis of Amyloidosis
Pages 333-341
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