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Advances in Surgical Pathology: Mesothelioma, a volume in the Advances in Surgical Pathology series, features chapters on current and impending changes in the field with an emphasis on practical issues, recent developments, and emerging concepts.
Created as a quick review, this volume delivers a concise, updated review of the pathological characteristics of mesothelioma—emphasizing the histologic correlation, clinical management, and treatment of the disease. Timely content features include recognition of precursor mesothelial lesions, the role of molecular biology in the diagnosis and prognosis of mesothelioma, the interface between the clinician and the surgical pathologist, and the legal implications of attributing disease origin to asbestos and other factors. The book provides a resource for the periodic updates in knowledge required for daily practice, for current credentialing, and for the self-assessment modules for recertification.
• Concise and practical format provides a quick review of mesothelioma ideal for residents, fellows, practicing pathologists, and clinicians.
• Core content addresses mesothelioma diagnosis, WHO classification, staging, imaging, biopsy, mimicking conditions, immunohistochemistry, targeted gene therapy, and the potential for stem cell treatment.
• Focus on recent advances and emerging technologies helps guide readers’ clinical care when treating patients with mesothelioma.
• Over 110 full-color images improve diagnostic accuracy.
Section 1: Epidemiology, Clinical, and Radiologic Features
Chapter 1: The Diagnosis of Mesothelioma
Timothy Craig Allen and Richard L. Attanoos
Chapter 2: WHO Classification
Richard L. Attanoos
Chapter 3: Staging
Jason Lester
Chapter 4: Imaging
Jason Lester
Chapter 5: Non-Asbestos-Related Diffuse Malignant Mesothelioma
Allen R. Gibbs and Richard L. Attanoos
Chapter 6: Spontaneous/Ideopathic Diffuse Malignant Mesothelioma
Allen R. Gibbs
Chapter 7: SV-40 Virus, Vaccines, and Disease
Richard L. Attanoos
Chapter 8: Medicolegal Considerations
Timothy Craig Allen and Richard L. Attanoos
Section 2: Histopathology
Chapter 9: Approach to the Serosal Biopsy
Richard L. Attanoos
Chapter 10: Morphologic Variants and their Mimics
Richard L. Attanoos and Allen R. Gibbs
Chapter 11: Mucin Histochemistry and Electron Microscopy
Richard L. Attanoos
Chapter 12: Immunohistochemistry
Richard L. Attanoos
Chapter 13: Atypical Mesothelial Proliferations
Timothy Craig Allen
Section 3: Molecular Features
Chapter 14: Molecular Mechanisms of Pathogenesis
Alain C. Borczuk
Chapter 15: Molecular Prognostic Markers
Jason Lester
Chapter 16: Targeted Gene Therapy
Jason Lester
Chapter 17: Immunotherapy
Jason Lester
Chapter 18: Molecular Diagnostics
Richard L. Attanoos
Chapter 19: Cancer Stem Cells
Timothy Craig Allen
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