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Libreria medica internazionale
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Advances in Surgical Pathology: Colorectal Carcinoma and Tumors of the Vermiform Appendix
130,00 €
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Advances in Surgical Pathology: Colorectal Carcinoma and Tumors of the Vermiform Appendix, a volume in the Advances in Surgical Pathology series, features chapters on current and impending changes in the field with an emphasis on practical issues, recent developments, and emerging concepts.

Created as a quick review to be used during pathologic evaluation of cancer specimens from the lower gastrointestinal tract, this book contains the latest information regarding emerging endoscopic techniques that aid in tumor classification and staging, mechanisms of pathogenesis, and clinical management. 

It combines gross and microscopic images and user-friendly tables for quick reference with a succinct, comprehensive review of issues important to management of patients with colorectal carcinoma. Not only does it discuss the applied concern of cancer epidemiology and prevention, the book also covers pathological features of cancer precursors. Plus, an introduction to future diagnostic and treatment modalities, such as biomarker analysis, chemotherapeutic strategies, targeted molecular therapies, and aggressive multidisciplinary approaches to patients with advanced stage disease. 


  • Emphasizes clinically and practically relevant information, including pathology reports and molecular test results
  • Covers relevant surgical anatomy, gross examination, and specimen preparation techniques to aid in the handling of surgical resection specimens   
  • Provides a basic knowledge of surgical pathology and molecular evaluation of colonic and appendiceal cancer

Section I. Introduction

1 Embryology, Anatomy, and Normal Histology of the Colorectum and Appendix
Debra Beneck
2 Epidemiology of Colorectal Adenocarcinoma
Karen Curtin
3 Screening and Surveillance for Prevention of Colorectal Carcinoma
Felice Schnoll-Sussman and Amir Soumekh

Section II. Cancer Precursors: Colorectal Polyps and Chronic Colitis

4 Epithelial Polyps and Inflammatory Bowel Disease–Related Dysplasia
Nicole C. Panarelli
5 Hamartomatous Polyps and Polyposis Syndromes
Rhonda K. Yantiss

Section III. Pathologic Features of Colorectal Carcinoma

6 Handling of Colorectal Cancer Resection Specimens
Rhonda K. Yantiss
7 Morphologic Classification of Colorectal Epithelial Tumors
Rhonda K. Yantiss
8 Pathologic Staging Issues: Implementation of the TNM Staging System
Rhonda K. Yantiss
9 Prognostically Important Features of Colorectal Carcinoma
Rhonda K. Yantiss
10 Differential Diagnosis of Colorectal Carcinoma
Rhonda K. Yantiss

Section IV. Molecular Pathology of Colorectal Carcinoma

11 Molecular Mechanisms of Colorectal Carcinogenesis
Jinru Shia and Rhonda K. Yantiss
12 Practical Issues Related to Ancillary Testing of Colorectal Carcinoma
Wade S. Samowitz
13 MicroRNA Expression in Colonic Adenocarcinoma
Nicole C. Panarelli
14 Noninvasive Biomarkers and Early Detection of Colorectal Cancer
Carl V. Crawford, Jr. and Rhonda K. Yantiss

Section V. Advances in the Management of Colorectal Carcinoma

15 Emerging Endoscopic Techniques in the Management of IBD-related Neoplasia
Nicole C. Panarelli, Ellen J. Scherl, and Rhonda K. Yantiss
16 Targeted Therapies for the Treatment of Advanced Colorectal Carcinoma
Allyson J. Ocean, Romae Palmer, and Manish A. Shah
17 Surgical Management of Stage IV Colorectal Cancer
Michael D. Kluger, Ser Yee Lee, and Daniel Cherqui

Section VI. Neoplasms of the Vermiform Appendix

18 Endocrine Cell (Carcinoid) Tumors of the Vermiform Appendix
Rhonda K. Yantiss
19 Appendiceal Mucinous Neoplasms and Pseudomyxoma Peritonei
Joseph Misdraji
20 Nonmucinous Epithelial Tumors of the Appendix
Rhonda K. Yantiss


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