Advances in Radiation Oncology in Lung Cancer 3rd edition

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Advances in Radiation Oncology in Lung Cancer 3rd edition

Editore

Springer

Anno

2023

Pagine

1165

ISBN

9783031348464

I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

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This is the third, completely updated edition of a comprehensive book in which many of the world’s leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings in lung cancer and other intrathoracic malignancies. Lung cancer remains the major cancer killer in both sexes worldwide. It is so despite significant progress in recent decades in both diagnostic and treatment approaches. New biological and technological advances in this field are now faster incorporated in the overall decision-making process and are bringing fast and substantial improvements in both survivals and quality of life of lung cancer patients. Optimized patient-oriented approaches are reality of the third decade of this millennium and thoracic oncologists strive towards nothing but seamlessly delivering it in a continuous battle with lung cancer.

The first three sections of the work cover the basic science of lung cancer, clinical investigations, including histology and staging, and a wide range of fundamental treatment considerations. Current treatment strategies for small cell and non-small cell lung cancer as well as other intrathoracic malignancies are then explained and evaluated in detail, with due attention to novel approaches that promise further improvements in outcome. The various types of treatment-related toxicity are discussed, and quality of life studies and prognostic factors are also considered. After evaluating the latest technological and biological advances, including stereotactic radiotherapy, and particle therapy, the book concludes by thorough consideration of specific aspects of clinical research in lung cancer.

This concise yet comprehensive book is an invaluable resource for radiation oncologists.

Front Matter

Pages i-xiv

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Basic Science of Lung Cancer
1. Front Matter
  
  Pages 1-1
  
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2. Genomic Alterations in Lung Cancer
  - Daniel Morgensztern
  Pages 3-16
3. Epigenetic Events in Lung Cancer
  - Octavio A. Romero, Montse Sanchez-Cespedes
  Pages 17-31
Clinical Investigations
1. Front Matter
  
  Pages 33-33
  
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2. Interventional Pulmonology
  - Branislav Perin, Bojan Zarić
  Pages 35-43
3. Pathology of Lung Cancer
  - Mari Mino-Kenudson
  Pages 45-65
4. Role of Radiologic Imaging in Lung Cancer
  - Salome Kukava, George Tsivtsivadze
  Pages 67-83
5. Place and Role of PET/CT in the Diagnosis and Staging of Lung Cancer
  - Salome Kukava, Michael Baramia
  Pages 85-111
6. Surgical Staging of Lung Cancer
  - Jarrod Predina, Douglas J. Mathisen, Michael Lanuti
  Pages 113-128
Basic Treatment Considerations
1. Front Matter
  
  Pages 129-129
  
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2. Surgical Workup and Management of Early-Stage Lung Cancer
  - Stephanie H. Chang, Joshua Scheinerman, Jeffrey Jiang, Darian Paone, Harvey Pass
  Pages 131-150
3. Radiation Biology of Lung Cancer
  - Jose G. Bazan
  Pages 151-169
4. Radiation Time, Dose, and Fractionation in the Treatment of Lung Cancer
  - David L. Billing, Andreas Rimner
  Pages 171-187
5. Optimizing Lung Cancer Radiotherapy Treatments Using Personalized Dose-Response Curves
  - Joseph O. Deasy, Jeho Jeong, Maria Thor, Aditya Apte, Andrew Jackson, Ishita Chen et al.
  Pages 189-212
6. Tumor Motion Control
  - Hiroki Shirato, Shinichi Shimizu, Hiroshi Taguchi, Seishin Takao, Naoki Miyamoto, Taeko Matsuura
  Pages 213-235
7. PET and PET/CT in Treatment Planning
  - Michael MacManus, Sarah Everitt, Rodney J. Hicks
  Pages 237-254
8. Target Volume Delineation in Non-small Cell Lung Cancer
  - Jessica W. Lee, Haijun Song, Matthew J. Boyer, Joseph K. Salama
  Pages 255-269
9. The Radiation Target in Small Cell Lung
  - Gregory M. M. Videtic
  Pages 271-284
10. Radiation Sensitizers
  - Mansi K. Aparnathi, Sami Ul Haq, Zishan Allibhai, Benjamin H. Lok, Anthony M. Brade
  Pages 285-302
Basic Treatment Considerations
1. Radioprotectors in the Management of Lung Cancer
  - Zhongxing Liao, Ting Xu, Ritsuko Komaki
  Pages 303-319
2. Chemotherapy for Lung Cancer
  - Mariam Alexander, Elaine Shum, Aditi Singh, Balazs Halmos
  Pages 321-346
3. Targeted Therapies in Non-small Cell Lung Cancer
  - Jessica R. Bauman, Martin J. Edelman
  Pages 347-369
4. Immunotherapy of Lung Cancer
  - Igor Rybkin, Shirish M. Gadgeel
  Pages 371-384
5. Combined Radiotherapy and Chemotherapy: Theoretical Considerations and Biological Premises
  - Michael K. Farris, Cole Steber, Corbin Helis, William Blackstock
  Pages 385-397
6. Mechanisms of Action of Radiotherapy and Immunotherapy in Lung Cancer: Implications for Clinical Practice
  - Kewen He, Ugur Selek, Hampartsoum B. Barsoumian, Duygu Sezen, Matthew S. Ning, Nahum Puebla-Osorio et al.
  Pages 399-414
Current Treatment Strategies in Early-Stage Non-small Cell Lung Cancer
1. Front Matter
  
  Pages 415-415
  
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2. Early Non-small Cell Lung Cancer: The Place of Radical Non-SABR Radiation Therapy
  - Tathagata Das, Matthew Hatton
  Pages 417-432
3. Never-Ending Story: Surgery Versus SBRT in Early-Stage NSCLC
  - James Taylor, Pamela Samson, William Stokes, Drew Moghanaki
  Pages 433-444
4. Stereotactic Ablative Radiotherapy for Early-Stage Lung Cancer
  - Dat T. Vo, John H. Heinzerling, Robert D. Timmerman
  Pages 445-470
5. Role of Postoperative Radiation Therapy in Non-Small Cell Lung Cancer
  - Alexander K. Diaz, Chris R. Kelsey
  Pages 471-482
6. The Role of Thermal Ablation in the Treatment of Stage I Non-small Cell Lung Cancer
  - Roberto B. Kutcher-Diaz, Aaron Harman, John Varlotto
  Pages 483-503
Current Treatment Strategies in Locally Advanced and Metastatic Non-small Cell Lung Cancer
1. Front Matter
  
  Pages 505-505
  
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2. Lung Dose Escalation
  - Kenneth E. Rosenzweig
  Pages 507-515
3. Multimodality Treatment of Stage IIIA/N2 NSCLC: Why Always NO to Surgery?
  - Branislav Jeremić, Ivane Kiladze, Slobodan Milisavljevic
  Pages 517-531
4. Multimodality Treatment of Stage IIIA/N2 Non-Small Cell Lung Cancer: When YES to Surgery
  - Sean All, David J. Sher
  Pages 533-545
5. Combined Radiation Therapy and Chemotherapy as an Exclusive Treatment Option in Locally Advanced Inoperable Non-small Cell Lung Cancer
  - Branislav Jeremić, Pavol Dubinsky, Slobodan Milisavljević, Ivane Kiladze
  Pages 547-569
6. Optimizing Drug Therapies in the Maintenance Setting After Radiochemotherapy in Non-small Cell Lung Cancer
  - Steven H. Lin, David Raben
  Pages 571-580
7. Prophylactic Cranial Irradiation in Non-small Cell Lung Cancer
  - Hina Saeed, Monica E. Shukla, Elizabeth M. Gore
  Pages 581-595
8. Palliative External Beam Thoracic Radiation Therapy of Non-small Cell Lung Cancer
  - Stein Sundstrøm
  Pages 597-604
Current Treatment Strategies in Locally Advanced and Metastatic Non-small Cell Lung Cancer
1. Intraoperative Radiotherapy in Lung Cancer: Methodology (Electrons or Brachytherapy), Clinical Experiences, and Long-Term Institutional Results
  - Felipe A. Calvo, Javier Aristu, Javier Serrano, Mauricio Cambeiro, Rafael Martinez-Monge, Rosa Cañón
  Pages 605-621
2. Brachytherapy for Lung Cancer
  - Raul Hernanz de Lucas, Teresa Muñoz Miguelañez, Alfredo Polo, Paola Lucia Arrieta Narvaez, Deisy Barrios Barreto
  Pages 623-636
3. Oligometastatic Disease: Basic Aspects and Clinical Results in NSCLC
  - Gukan Sakthivel, Deepinder P. Singh, Haoming Qiu, Michael T. Milano
  Pages 637-648
Current Treatment Strategies in Small Cell Lung Cancer
1. Front Matter
  
  Pages 649-649
  
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2. Radiation Therapy in Limited Disease Small Cell Lung Cancer
  - Branislav Jeremić, Ivane Kiladze, Pavol Dubinsky, Slobodan Milisavljević
  Pages 651-666
3. Role of Thoracic Radiation Therapy in Extensive Disease Small Cell Lung Cancer
  - Branislav Jeremić, Mohamed El-Bassiouny, Ramy Ghali, Ivane Kiladze, Sherif Abdel-Wahab
  Pages 667-676
4. Prophylactic Cranial Irradiation in Small Cell Lung Cancer
  - William G. Breen, Yolanda I. Garces
  Pages 677-687
Treatment in Specific Patient Groups and Other Settings
1. Front Matter
  
  Pages 689-689
  
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2. Radiation Therapy for Lung Cancer in Elderly
  - Erkan Topkan, Ugur Selek, Berrin Pehlivan, Ahmet Kucuk, Yasemin Bolukbasi
  Pages 691-715
3. Radiation Therapy for Intrathoracic Recurrence of Lung Cancer
  - Yukinori Matsuo, Hideki Hanazawa, Noriko Kishi, Kazuhito Ueki, Takashi Mizowaki
  Pages 717-737
4. Treatment of Second Lung Cancers
  - Reshad Rzazade, Hale Basak Caglar
  Pages 739-753
5. Radiation Therapy for Brain Metastases
  - Dirk Rades, Sabine Bohnet, Steven E. Schild
  Pages 755-777
6. Radiation Therapy for Metastatic Lung Cancer: Bone Metastasis and Metastatic Spinal Cord Compression
  - Begoña Taboada-Valladares, Patricia Calvo-Crespo, Antonio Gómez-Caamaño
  Pages 779-793
7. Radiation Therapy for Metastatic Lung Cancer: Liver Metastasis
  - Fiori Alite, Anand Mahadevan
  Pages 795-807
8. Advances in Supportive and Palliative Care for Lung Cancer Patients
  - Michael J. Simoff, Javier Diaz-Mendoza, A. Rolando Peralta, Labib G. Debiane, Avi Cohen
  Pages 809-829
Other Intrathoracic Malignancies
1. Front Matter
  
  Pages 831-831
  
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2. Thymic Cancer
  - Gokhan Ozyigit, Pervin Hurmuz
  Pages 833-848
3. Advances in Radiation Therapy for Malignant Pleural Mesothelioma
  - Gwendolyn M. Cramer, Charles B. Simone II, Theresa M. Busch, Keith A. Cengel
  Pages 849-861
4. Primary Tracheal Tumors
  - Shrinivas Rathod
  Pages 863-877
5. Pulmonary Carcinoid
  - Roshal R. Patel, Brian De, Vivek Verma
  Pages 879-904
Treatment-Related Toxicity
1. Front Matter
  
  Pages 905-905
  
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2. Hematological Toxicity in Lung Cancer
  - Francesc Casas, Diego Muñoz-Guglielmetti, Gabriela Oses, Carla Cases, Meritxell Mollà
  Pages 907-923
3. Radiation Therapy-Induced Lung and Heart Toxicity
  - Soheila F. Azghadi, Megan E. Daly
  Pages 925-939
4. Spinal Cord
  - Timothy E. Schultheiss
  Pages 941-954
5. Radiation Therapy-Related Toxicity: Esophagus
  - Srinivas Raman, Meredith Giuliani
  Pages 955-967
6. Brain Toxicity
  - C. Nieder
  Pages 969-983
Quality of Life Studies and Prognostic Factors
1. Front Matter
  
  Pages 985-985
  
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2. Patient-Reported Outcomes in Lung Cancer
  - Newton J. Hurst Jr, Farzan Siddiqui, Benjamin Movsas
  Pages 987-999
3. Importance of Prognostic Factors in Lung Cancer
  - Lukas Käsmann
  Pages 1001-1017
Technological Advances in Lung Cancer
1. Front Matter
  
  Pages 1019-1019
  
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2. Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy for Lung Cancer
  - Jacob S. Parzen, Inga S. Grills
  Pages 1021-1047
3. Image-Guided Radiotherapy in Lung Cancer
  - Julius Weng, Patrick Kupelian, Percy Lee
  Pages 1049-1058
4. Heavy Particles in Non-small Cell Lung Cancer: Protons
  - Charles B. Simone II
  Pages 1059-1074
5. Heavy Particles in Non-small Cell Lung Cancer: Carbon Ions
  - S. Tubin, P. Fossati, S. Mori, E. Hug, T. Kamada
  Pages 1075-1091
6. The Role of Nanotechnology for Diagnostic and Therapy Strategies in Lung Cancer
  - Jessica E. Holder, Minnatallah Al-Yozbaki, Cornelia M. Wilson
  Pages 1093-1110
Clinical Research in Lung Cancer
1. Front Matter
  
  Pages 1111-1111
  
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2. Translational Research in Lung Cancer
  - Haoming Qiu, Michael A. Cummings, Yuhchyau Chen
  Pages 1113-1133
3. Radiation Oncology of Lung Cancer: Why We Fail(ed) in Clinical Research?
  - Branislav Jeremić, Nenad Filipović, Slobodan Milisavljević, Ivane Kiladze
  Pages 1135-1145
4. Randomized Clinical Trials: Pitfalls in Design, Analysis, Presentation, and Interpretation
  - Lawrence Kasherman, S. C. M. Lau, K. Karakasis, N. B. Leighl, A. M. Oza
  Pages 1147-1165