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Genetics in Asthma
Pages 3-14
This book provides discussions on bronchial asthma from a clinical perspective, focusing on the recent studies on its pathophysiology, diagnosis and treatment. It also explores the lastest findings regarding the phenotypes and endotypes of asthmatic patients, making it of particular interest to those involved with non-eosinophilic asthma and eosinophilic asthma. Further, it discusses the importance of ILC 2 in eosinophilic asthma, and the accumulated results from the forced oscilliation technique and periostin that are actively practiced in Japan. As some aspects of diagnosis and treatment are different in Western and Asian countries, it is important that the data is disseminated around the globe.
The clinical questions addressed by the authors are critical and thought provoking, while the questions raised by the editors are instructive, informative and provide new perspectives on unresolved issues. This book appeals to wide readership from beginning learners to physicians in clinical practice and scholars engaging in basic research.
Genetics in Asthma
Pages 3-14
Group 2 Innate Lymphoid Cells and Asthma
Pages 15-25
Cellular Mechanisms of Allergic Airway Inflammation
Pages 27-39
Mechanisms for Non-eosinophilic Asthma
Pages 41-52
Corticosteroid Resistance in Asthma
Pages 53-61
Asthma Phenotype and Endotype
Pages 65-70
Periostin as a Biomarker for Type 2 Asthma
Pages 71-81
Clinical Application of the Forced Oscillation Technique (FOT)
Pages 83-92
Diagnostic Value of Fractional Exhaled Nitric Oxide (FeNO)
Pages 93-100
Aspirin-Exacerbated Respiratory Disease (AERD)
Pages 101-113
Essence of the Japanese Guidelines for Adult Asthma
Pages 117-131
How to Improve Adherence Technique for Inhaler Use and Selection of Inhalers
Pages 133-144
Treatment with Anti-IgE Monoclonal Antibody and Free IgE
Pages 145-156
Bronchial Thermoplasty: Japanese Experiences
Pages 157-165
Asthma COPD Overlap (ACO)
Pages 167-175
Future Treatment and Other New Biologics for Asthma
Pages 177-189
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