Table of Contents

Preface vii

Foreword ix

Editor biographies x

Contributors xi

SECTION 1 Physiology and function of the gastrointestinal and hepatobiliary tract 1

1.1 Physiology and function of the mouth 3

1.2 Physiology and function of the oesophagus 8

1.3 Physiology and function of the stomach 15

1.4 Physiology and function of the small intestine 21

1.5 Physiology and function of the colon 28

1.6 Physiology and function of the pancreas 33

1.7 Physiology and function of the hepatobiliary tract 36

1.8 Gastrointestinal microbiota 41

1.9 Gastrointestinal tract and appetite control 48

SECTION 2 Dietary components relevant to gastrointestinal health 55

2.1 Fibre and gastrointestinal health 57

2.2 Short-chain fermentable carbohydrates 72

2.3 Probiotics and the gastrointestinal microbiota 81

2.4 Prebiotics and gastrointestinal health 87

SECTION 3 Gastrointestinal disorders 93

3.1 Orofacial granulomatosis and nutrition 95

3.2 Eosinophilic oesophagitis and nutrition 101

3.3 Gastro-oesophageal reflux disease and nutrition 105

3.4 Oesophageal cancer and nutrition 111

3.5 Gastric cancer and nutrition 118

3.6 Gastroparesis and nutrition 127

3.7 Pancreatitis and nutrition 132

3.8 Pancreatic cancer and nutrition 140

3.9 Cystic fibrosis and nutrition 147

3.10 Lymphangiectasia and nutrition 155

3.11 Coeliac disease and nutrition 160

3.12 Inflammatory bowel disease pathogenesis 169

3.13 Inflammatory bowel disease nutritional consequences 180

3.14 Inflammatory bowel disease dietary management 191

3.15 Lactose malabsorption and nutrition 202

3.16 Intestinal failure and nutrition 210

3.17 Stomas and nutrition 218

3.18 Irritable bowel syndrome pathogenesis 226

3.19 Irritable bowel syndrome dietary management 233

3.20 Diverticular disease and nutrition 243

3.21 Constipation and nutrition 249

3.22 Colorectal cancer and nutrition 255

SECTION 4 Hepatobiliary disorders 263

4.1 Gallbladder disease and nutrition 265

4.2 Primary biliary cirrhosis and primary sclerosing cholangitis and nutrition 273

4.3 Alcohol-related liver disease and nutrition 280

4.4 Autoimmune hepatitis and viral hepatitis and nutrition 284

4.5 Non-alcoholic fatty liver disease and hereditary haemochromatosis and nutrition 290

4.6 Decompensated liver disease and nutrition 296

4.7 Hepatocellular carcinoma and nutrition 309

4.8 Liver transplantation and nutrition 311

Index 317