Titolo: Acute Myeloid Leukemia in Children

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Oncologia e Radioterapia

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Acute Myeloid Leukemia in Children

Standard of Care and Future Perspectives

Editore

Springer

Anno

2024

Pagine

342

ISBN

9783031633652

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This book provides up-to-date information on key topics and issues in Pediatric Acute Myeloid Leukemia (AML), including the epidemiology, biology, diagnosis and treatment of particular forms of the disease, supportive care, and survivorship. The entire spectrum of clinical management on pediatric AML is covered with the aim of equipping readers with the latest knowledge relevant to clinical practice and research, based on enormous efforts made by cooperative clinical trial groups and consortia worldwide. Each chapter is written by internationally renowned authorities who have been selected for their expertise in the subjects discussed. This book will serve pediatric hematologists/oncologists, fellows, and residents both as a comprehensive source of information and as a quick reference. The book will also be of interest to pediatricians and general practitioners.

Front Matter

Pages i-viii

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Epidemiology and Biology of Pediatric AML
1. Front Matter
  
  Pages 1-1
  
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2. Overview and Epidemiology of Pediatric AML
  - D. Spencer Mangum, Edward Anders Kolb
  Pages 3-18
3. Chromosomal and Genomic Alterations in Pediatric AML
  - Adam Lamble, Benjamin Huang
  Pages 19-36
4. Germline Predisposition to MDS and AML
  - Majd Khiami, Marcin Wlodarski
  Pages 37-55
Diagnosis of Pediatric AML
1. Front Matter
  
  Pages 57-57
  
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2. Diagnosis and Classifications of Pediatric AML
  - Linda Fogelstrand, Dirk Reinhardt
  Pages 59-77
3. Measurable Residual Disease Assessment in Pediatric AML
  - Martina Pigazzi, Claudia Tregnago, Chad A. Hudson, Lisa Eidenschink Brodersen
  Pages 79-101
Advances in Treatment of Pediatric AML
1. Front Matter
  
  Pages 103-103
  
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2. De Novo AML
  - Todd Cooper, Dirk Reinhardt, Daisuke Tomizawa
  Pages 105-122
3. Extramedullary Leukemia in Pediatric AML
  - Matthew A. Kutny
  Pages 123-131
4. Acute Promyelocytic Leukemia
  - Oussama Abla, Hau C. Kwaan
  Pages 133-159
5. Myeloid Proliferation Associated with Down Syndrome (ML-DS, TAM)
  - Jan-Henning Klusmann, Milica Miladinovic, Johann Hitzler, Takashi Taga
  Pages 161-176
6. Myeloproliferative Disorders in Non-Down Syndrome Patients
  - Bianca F. Goemans, Jessica A. Pollard
  Pages 177-191
7. AML in Distinct Age-Defined Populations of Infants, Adolescents and Young Adults
  - Stephanie H. Guarino, Erin M. Guest
  Pages 193-209
8. Myeloid Neoplasms Postcytotoxic Therapy in Children
  - Neerav Shukla
  Pages 211-219
9. Advanced MDS in Children
  - Daisuke Hasegawa, Henrik Hasle
  Pages 221-229
10. Refractory/Relapsed AML in Children and Evolution of Novel Therapies
  - Kristian L. Juul-Dam, Sae Ishimaru, Valeria Ceolin, C. Michel Zwaan
  Pages 231-254
11. Stem Cell Transplantation and Cellular Immunotherapies for Pediatric AML
  - Naghmeh Niktoreh, Sarah K Tasian, Krzysztof Kalwak
  Pages 255-279
12. Pediatric AML in Resource-Limited Countries
  - Noa E. Wijnen, Festus Njuguna, Gertjan J. L. Kaspers
  Pages 281-292

Supportive Issues in Pediatric AML
1. Front Matter
  
  Pages 293-293
  
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2. Infection Management in Pediatric AML
  - Jennifer Wilkes
  Pages 295-305
3. Cardiotoxicity in Pediatric AML
  - Kasey J. Leger, Hari K. Narayan
  Pages 307-325
4. Late Effects in Pediatric AML Survivors
  - Neel S. Bhatt, Daniel A. Mulrooney
  Pages 327-342