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The new edition of this well-received book provides a timely update of current knowledge on the biology, disease classification, and treatment of the acute leukemias – acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Throughout, the focus is on the provision of state of the art information and guidance that will meet the needs of clinicians. Chapters have been extensively revised to take into account advances in understanding and management that have been achieved over the past few years. In addition, new chapters have been included on selection of AML patients for therapy, a broader discussion of stem cell transplantation in AML, the role of immunotherapy in ALL, the approach to newly diagnosed pediatric ALL, and the diagnosis and management of BCR-ABL-like ALL. New therapies, including investigational ones, are fully covered. As progress continues in the management of acute leukemias this book will be a valuable asset for clinicians at all levels of experience.
Acute Myeloid Leukemia: Epidemiology and Etiology
Pages 3-9
Sweet, Kendra (et al.)
Clinical Presentation, Diagnosis, and Classification of Acute Myeloid Leukemia
Pages 11-55
Juskevicius, Ridas (et al.)
Insights into the Pathobiology of Secondary AML
Pages 57-68
Jain, Tania (et al.)
Selection of Patients for Individual Acute Myeloid Leukemia Therapies
Pages 69-75
Walter, Roland B.
Therapy of Newly Diagnosed Acute Myeloid Leukemia (AML)
Pages 77-87
Halpern, Anna B. (et al.)
Management of Relapsed/Refractory Acute Myeloid Leukemia
Pages 89-109
Jammal, Nadya (et al.)
The Role of Stem Cell Transplant in the Therapy of Acute Myeloid Leukemia (AML)
Pages 111-131
Sanford, David (et al.)
Novel and Investigational Therapies in Acute Myeloid Leukemia
Pages 133-144
Immune-Based Approaches in AML
Pages 145-153
Alotaibi, Ahmad S. (et al.)
Acute Lymphoblastic Leukemia: Clinical Presentation, Diagnosis, and Classification
Pages 157-167
Gurbuxani, Sandeep (et al.)
Frontline Therapy of Newly Diagnosed Acute Lymphoblastic Leukemia
Pages 169-184
Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents
Pages 185-192
Hematopoietic Cell Transplantation (HCT) for Acute Lymphoblastic Leukemia (ALL)
Pages 193-204
Poon, Limei Michelle (et al.)
Minimal or Measurable Residual Disease in Acute Lymphoblastic Leukemia
Pages 205-218
Paul, Shilpa (et al.)
Management of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Pages 219-233
Chew, Serena (et al.)
Ph-Like ALL: Diagnosis and Management
Pages 235-247
Curran, Emily K. (et al.)
Adult Burkitt Leukemia/Lymphoma
Pages 249-275
Abdayem, Pamela (et al.)
Management of Relapsed and Refractory ALL
Pages 277-289
Kishtagari, Ashwin (et al.)
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