Informazioni
Non ci sono recensioni
Cancer Overdiagnosis and Overtreatment
Pages 1-8
Punto di Riferimento
per Medici e Operatori Sanitari
per Medici e Operatori Sanitari
LIBRERIA STUDIUM
Active Surveillance for Localized Prostate Cancer
A New Paradigm for Clinical Management
Klotz
Anno
2018
Pagine
250
ISBN
9783319627090
90,00 €
DA SCONTARE
This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the role of biomarkers and MRI in patient selection and management and details the world wide results of active surveillance. Specific chapters address communication and ethical issues, QOL outcomes, economic aspects, and psycho-social aspects of surveillance. The role of focal therapy for low risk disease is summarized, and the data supporting preventive interventions during surveillance reviewed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in this common malignancy, as it provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.
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Can We Screen and Still Reduce Overdiagnosis?
Pages 9-20
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The Role of Fear in Overdiagnosis and Overtreatment
Pages 21-29
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Ethical and Legal Considerations in Active Surveillance for Prostate Cancer
Pages 31-39
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Gleason 6 Tumors Should Still Be Labeled as Cancer
Pages 41-52
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Risk-Based Selection for Active Surveillance
Pages 53-64
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Surveillance at the Margins: Management of High-Volume Gleason 6, PSA > 10, or Gleason 3 + 4
Pages 65-69
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How Should Patients on Active Surveillance Be Followed?
Pages 71-81
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Triggers for Intervention
Pages 83-94
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MR Imaging in Prostate Tumor Volume Assessment: How Accurate?
Pages 95-109
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Can MRI Replace Biopsy in Men on Surveillance?
Pages 111-119
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Tissue-Based Markers for Risk Prediction
Pages 121-133
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International AS Registry: The Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance Initiative
Pages 135-147
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Better-Informed Decision-Making to Optimize Patient Selection
Pages 149-167
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How Does QoL Compare Between Surveillance and Active Treatment?
Pages 169-181
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The Potential Benefits of Diet and Physical Activity Among Active Surveillance Patients with Low-Burden Prostate Cancer
Pages 183-198
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Is There a Role for Pharmacologic Manipulation to Prevent Progression in Men on Active Surveillance? The Role of 5-ARIs, Statins, and Metformin
Pages 199-206
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The Update of Active Surveillance Around the World: Utilization and Outcomes
Pages 207-216
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Tissue Preservation: Active Surveillance and Focal Therapy as Complimentary Strategies
Pages 217-227
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The Economics of Active Surveillance for Prostate Cancer
Pages 229-237
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Research Questions in Active Surveillance
Pages 239-241
