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This book provides a state-of-the-art overview of the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic disorders. The opening section covers clinical tools with a particular focus on the role of electromyography and MRI imaging. The second section then presents the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, discussing in detail relevant clinical conditions such as including myasthenia gravis, polymyositis, and statin myopathies. The third section examines acute and chronic immune-mediated neuropathies, multifocal motor neuropathies, amyotrophic lateral sclerosis, paraneoplastic diseases, and diabetic polyneuropathy, offering clear guidance on available treatments and descriptions of the latest advances in immunotheraphy, drug therapy, and physiotherapy. This clinically oriented book also includes numerous illustrative figures and contributions by international authors from leading centers.
Pages i-xiv
Front Matter
Pages 1-1
Autoantibodies in Neuromuscular Disorders
Pages 3-24
Pages 25-41
Imaging of the Muscle in Idiopathic Inflammatory Myopathies
Pages 43-61
Ultrasound Evaluation of Peripheral Nerves: Evidence, Clinical Application, and Recent Developments
Pages 63-81
Magnetic Resonance Imaging of the Peripheral Nerve
Pages 83-103
Front Matter
Pages 105-105
Pages 107-121
Necrotizing Autoimmune Myopathy
Pages 123-135
Pages 137-147
Pages 149-162
Pages 163-177
Vitamin D Deficiency in Muscle
Pages 179-188
Intensive Care Unit-Acquired Weakness
Pages 189-212
Acquired Immune-Mediated Rippling Muscles With and Without Myasthenia Gravis
Pages 213-229
Front Matter
Pages 231-231
Pages 233-248
Pages 249-294
Amyotrophic Lateral Sclerosis: Neurochemical Biomarkers
Pages 295-310
Paraneoplastic Diseases of the Peripheral Nervous System
Pages 311-324
Pages 325-342
Pages 343-359
Pages 361-372
Pages 373-382
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