A Manual for Cervical Cancer Screening and Control: Principles, Practice and New Perspectives

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Autore: Branca, Filho
Editore: Nova Publishers
Anno: 2014
Pagine: 315
ISBN: 9781634630108
Prezzo: 90,00€
I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.


Cervical cancer (CC) is a major global health problem. Worldwide, an estimated 530,000 new cases of CC and 275,000 deaths from this disease are encountered every year. CC affects particularly women less than 45 years of age and it is the leading cause of cancer-related deaths among women in the developing and underdeveloped countries, where 60–80% of cases are detected in advanced stages. After Human Papillomavirus (HPV) identification as the infectious etiological agent and elucidation of the natural history of CC, this tumor has become the most preventable and curable of all cancers. Well-organized screening programs with Papanicolaou (Pap) smear are known to be successful in decreasing both mortality and morbidity of this disease. This book describes the optional screening programs for CC prevention, whether organized, opportunistic or spontaneous and also their merits and weaknesses. Monitoring of the pathways and procedures of CC screening are mandatory in order to minimise the risks (wrong diagnosis, over-diagnosis, over-treatment) and maximize the benefits. In an optimal setting, the women should be the focus of the screening intervention and receive basic information on the crucial points of CC screening, so as to improve women’s collaboration and compliance. The availability of alternative new screening tools to detect pre-cancer lesions provide new opportunities for CC prevention, as do HPV vaccines implemented in early life before viral exposure. This book, rich in pictures, tables and flowcharts is a comprehensive treatise on CC screening: its 14 chapters illustrate the fundamental principles and the necessary interventions for CC prevention and control and a guide for all medical and paramedical professionals involved in the interplay of CC screening.

Table of Contents:

Preface pp. i-ix

Acknowledgments pp.xi

Chapter 1. The global burden of cervical cancer pp. 1-18

Chapter 2. Opportunities for cervical cancer prevention: the primary prevention pp. 19-32

Chapter 3. Human Papillomavirus (HPV) infections pp. 33-44

Chapter 4. Risk factors for cervical cancer pp. 45-54

Chapter 5. Secondary prevention with screening programs pp. 55-82

Chapter 6. Cancer prevention in developing countries pp. 83-92

Chapter 7. Cervical cytology and alternative methods of screening pp. 93-106

Chapter 8. Management of women with abnormal cytological results pp. 107-134

Chapter 9. Use of biomarkers in cervical cancer screening pp. 135-166

Chapter 10. Basic concepts of quality and accreditation in Health Care Services pp. 167-184

Chapter 11. Quality issues in screening test procedures pp. 185-218

Chapter 12. Quality issues in the cervical cancer screening program: indicators and standards pp. 219-240

Chapter 13. Instruction and training of personnel in a cervical cancer screening program pp. 241-264

Chapter 14. Universal hygienic measures and precautions for infection prevention in gynecological ambulatory centers and hospitals pp. 265-278

Glossary pp. 279-288

Index pp. 291-304

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