Precision in Pulmonary, Critical Care, and Sleep Medicine

A Clinical and Research Guide

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Autore: Gomez, Himes, Kaminski
Editore: Springer
Anno: 2020
Pagine: 471
ISBN: 9783030315061
Prezzo: 130,00€
I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine. It combines fundamental concepts of the field with state-of-the-art studies and how they translate into individual preventive, diagnostic and therapeutic plans.


Precision medicine is focused on the integration of individual variability with disease prevention and treatment principles derived from population studies. This concept has risen to prominence in recent years in parallel with advances in genetics, molecular diagnostics and novel target-specific therapies. This fundamental shift in the approach to treatment has broad implications in how we prevent, diagnose and treat disease. Describing key concepts of precision medicine and relating these to pulmonary, critical care and sleep disorders is essential to educate relevant stakeholders and increase the impact of pulmonary precision medicine.


The book is organized into seven sections: introduction; genetics; biomarkers; precise phenotyping; mobile health, wearables and telemedicine; precision therapeutics; and enabling widespread adoption of precision medicine. The chapters are organized with an introduction to the specific theme, followed by its basic concepts. They then delve into how these basic concepts relate to the larger theme of precision medicine, new precision medicine approaches to dealing with these problems, and key takeaway points. Liberally illustrated with images, figures, and tables, the text is thorough and intuitive for clinicians and researchers to learn the processes and applications of precision medicine.



This is an ideal guide for clinicians to learn new precision medicine concepts in the fields of genetics, genomics, mobile health, and how they apply to their practice and their patients, as well as researchers seeking a basic understanding of precision medicine to assist in designing future research studies.

  • Introduction

    Pages 3-8

    Gomez, Jose L. (et al.)

  • Differential Diagnosis of Diffuse Pulmonary Disorders Using Genetics

    Pages 11-23

    Kropski, Jonathan A.

  • Genetics and Pharmacogenetics of Asthma

    Pages 25-37

    Kan, Mengyuan (et al.)

  • Genetics and Pharmacogenetics of COPD

    Pages 39-55

    Bossé, Yohan (et al.)

  • The Evolution of Precision Medicine in Cystic Fibrosis

    Pages 57-69

    Kunitomo, Yukiko (et al.)

  • Genetics of Idiopathic Pulmonary Fibrosis

    Pages 71-85

    Mathai, Susan K. (et al.)

  • Genetics of Lung Cancer

    Pages 87-103

    Steiling, Katrina (et al.)

  • Chest Imaging for Precision Medicine

    Pages 107-115

    Ash, Samuel Y. (et al.)

  • Biobanking for Pulmonary, Critical Care, and Sleep Medicine

    Pages 117-130

    Winkler, Julia (et al.)

  • Biomarkers in Obstructive Airway Diseases

    Pages 131-153

    Kelly, Rachel S. (et al.)

  • Biomarkers in Interstitial Lung Diseases

    Pages 155-165

    Fernandez, Isis E. (et al.)

  • Molecular Diagnostics in Pulmonary Infections

    Pages 167-184

    Gao, Catherine A. (et al.)

  • Biomarkers in Critical Care Illness: ARDS and Sepsis

    Pages 185-198

    Lambden, Simon P. F. (et al.)

  • Lessons for Precision Medicine from Lung Cancer

    Pages 201-223

    Bade, Brett C. (et al.)

  • COPD Phenotyping

    Pages 225-239

    O’Brien, Emmet (et al.)

  • Precision Medicine in Pulmonary Hypertension

    Pages 241-255

    Singh, Inderjit (et al.)

  • Identifying Subtypes of Obstructive Sleep Apnea

    Pages 257-266

    Pack, Allan I.

  • Precision Medicine in Critical Illness: Sepsis and Acute Respiratory Distress Syndrome

    Pages 267-288

    Rogers, Angela J. (et al.)

  • Mobile Applications and Wearables for Chronic Respiratory Disease Monitoring

    Pages 291-304

    Wu, Ann Chen (et al.)

  • Personal Environmental Monitoring

    Pages 305-320

    Xie, Sherrie (et al.)

  • Tele-ICU in Precision Medicine: It’s Not What You Do, But How You Do It

    Pages 321-331

    Marshall, Peter S.

  • Lung Transplantation and Precision Medicine

    Pages 335-353

    Beeckmans, Hanne (et al.)

  • Precision in Mechanical Ventilation

    Pages 355-367

    Dugan, Karen C. (et al.)

  • Precision Medicine for Cigarette Smoking Addiction

    Pages 369-381

    Baldassarri, Stephen R.

  • Implementing COPD Precision Medicine in Clinical Practice

    Pages 383-392

    Sin, Don D.

  • Precision Medicine for All: Minority Health

    Pages 395-407

    Ortega, Victor E. (et al.)

  • Education for the Practice of Precision Medicine in PCCSM: Creating Tomorrow’s Workforce

    Pages 409-416

    Honiden, Shyoko (et al.)

  • Summary and Future Applications of Precision Medicine in Pulmonary, Critical Care, and Sleep Medicine

    Pages 417-428

    Gomez, Jose L. (et al.)

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