Meningitis and Encephalitis

Management and Prevention Challenges

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Autore: Hasbun
Editore: Springer
Anno: 2019
Pagine: 238
ISBN: 9783319926773
Prezzo: 120,00€
I prezzi indicati possono subire variazioni poiché soggetti all'oscillazione dei cambi delle valute e/o agli aggiornamenti effettuati dagli Editori.

Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae.  The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs,  overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases.  Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed.
This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, including healthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients.
Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.

  • Introduction

    Hasbun, Rodrigo

    Pages 1-4

  • Community-Acquired Acute Bacterial Meningitis

    Glimaker, Martin

    Pages 5-25

  • Healthcare-Acquired Meningitis and Ventriculitis

    Bravo, Tricia (et al.)

    Pages 27-42

  • Acute Aseptic Meningitis Syndrome

    Hasbun, Rodrigo

    Pages 43-55

  • Cryptococcal Meningitis

    Al Hammadi, Ahmed (et al.)

    Pages 57-77

  • Challenges in Tuberculous Meningitis

    Starke, Jeffrey R. (et al.)

    Pages 79-96

  • Neurobrucellosis

    Enani, Mushira Abdulaziz

    Pages 97-106

  • West Nile Encephalitis

    McKenna, Megan (et al.)

    Pages 107-124

  • Herpes Simplex and Varicella Zoster Virus

    Bloch, Karen C., MD, MPH

    Pages 125-140

  • Human Immunodeficiency Virus (HIV)-Associated CD8 Encephalitis

    Woods, Steven Paul (et al.)

    Pages 141-151

  • Challenges in the Management and Prevention of Japanese Encephalitis

    Kaewpoowat, Quanhathai (et al.)

    Pages 153-174

  • Autoimmune Encephalitis

    Venkatesan, Arun (et al.)

    Pages 175-190

  • Neurosyphilis

    Kulkarni, Prathit A. (et al.)

    Pages 191-205

  • Neuroborreliosis

    Halperin, John J.

    Pages 207-216

  • Emerging Causes of Encephalitis: Zika, Dengue, Chikungunya, and Beyond

    Figueiredo, Mario Luis Garcia (et al.)

    Pages 217-227


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