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Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition

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Autore: Rifai
Editore: Elsevier
Anno: 2019
Pagine: 1088
ISBN: 9780323530446
Prezzo: 114,00€
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Get the foundational knowledge you need to successfully work in a real-world, clinical lab with Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition. From highly respected clinical chemistry expert Nader Rifai, this condensed, easier-to-understand version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics uses a laboratory perspective to guide you through selecting and performing diagnostic lab tests and accurately evaluating the results. Coverage includes laboratory principles, analytical techniques, instrumentation, analytes, pathophysiology, and more. This eighth edition features new clinical cases from The Coakley Collection, new questions from The Deacon’s Challenge of Biochemical Calculations Collection, plus new content throughout the text to ensure you stay ahead of all the latest techniques, instrumentation, and technologies.

Features:
  • Condensed version of the clinical chemistry "bible" offers the same authoritative and well-presented content in a much more focused and streamlined manner.
  • Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing.
  • Updated chapters on molecular diagnostics cover the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field.
  • Learning objectives, key words, and review questions are included in each chapter to support learning.
  • More than 500 illustrations plus easy-to-read tables help readers better understand and remember key concepts.
New To This Edition:
  • NEW! Clinical Cases from The Coakley Collection use real-life scenarios to demonstrate how concepts from the text will come in to play in real life practice.
  • NEW! Questions from The Deacon’s Challenge of Biochemical Calculations Collection help reinforce concepts and help readers’ critical thinking skills.
  • NEW! Updated content throughout the text keeps readers up to date on the latest techniques, instrumentation, and technologies.
  • NEW! New lead author Nader Rifai lends his expertise as the Director of Clinical Chemistry at Children’s Hospital in Boston, the Editor-in-Chief of the journal Clinical Chemistry, and a Professor of Pathology at Harvard University.

 

PART I: PRINCIPLES OF LABORATORY MEDICINE
1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
2. Analytical and Clinical Evaluation of Methods
3. Preanalytical Variation
4. Biological Variation
5. Establishment and Use of Reference Values
6. Specimen Collection, Processing, and Other Preanalytical Variables
7. Quality Management
8. Principles of Basic Techniques and Laboratory Safety

PART II: ANALYTICAL TECHNIQUES AND INSTRUMENTATION
9. Optical Techniques 
10. Electrochemistry and Chemical Sensors
11. Electrophoresis
12. Chromatography 
13. Mass Spectrometry 
14. Enzyme and Rate Analyses 
15. Immunochemical Techniques 
16. Automation
17. Point-of-Care Testing

PART III:  ANALYTES
18. Amino Acids, Peptides, and Proteins
19. Serum Enzymes
20. Tumor Markers
21. Kidney Function Tests - Creatinine, GFR, Urea, and Uric Acid
22. Carbohydrates
23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
24. Electrolytes and Blood Gases
25. Hormones
26. Catecholamines and Serotonin
27. Vitaminsand Trace Elements,
28. Hemoglobin, Iron, and Bilirubin
29. Porphyrins and Porphyrias 
30. Therapeutic Drug  Monitoring
31. Clinical Toxicology 
32. ToxicElements

PART IV:  PATHOPHYSIOLOGY
33. Diabetes Mellitus
34. Cardiovascular Disease
35. Kidney Disease 
36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
37. Liver Disease 
38. Gastrointestinal and Pancreatic Diseases  
39. Disorders of Bone and Mineral Metabolism
40. Disorders of the Pituitary Gland
41. Disorders of the Adrenal Cortex 
42. Thyroid Disorders
43. Reproduction-Related Disorders 
44. Pregnancy and Prenatal Testing 
45. Newborn Screening and Inborn Errors of Metabolism
46. Pharmacogenetics

PART V:  MOLECULAR DIAGNOSTICS  
47. Molecular Principles
48. Molecular Techniques
49. Molecular Applications

Appendix Reference Information for the Clinical Laboratory

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